KARRIKIN UP-REGULATED F-BOX 1 (KUF1) Imposes Negative Feedback Regulation of Karrikin and KAI2 Ligand Metabolism in

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2022 Mar 7

PMID 35254909

Authors

Claudia Sepulveda

Michael A Guzman

Qingtian Li

Jose Antonio Villaecija-Aguilar

Stephanie E Martinez

Muhammad Kamran

Aashima Khosla

Wei Liu

Joshua M Gendron

Caroline Gutjahr

Mark T Waters

David C Nelson

Affiliations

Soon will be listed here.

Abstract

SignificanceKarrikins are chemicals in smoke that stimulate regrowth of many plants after fire. However, karrikin responses are not limited to species from fire-prone environments and can affect growth after germination. Putatively, this is because karrikins mimic an unknown signal in plants, KAI2 ligand (KL). Karrikins likely require modification in plants to become bioactive. We identify a gene, , that appears to negatively regulate biosynthesis of KL and metabolism of a specific karrikin. expression increases in response to karrikin or KL signaling, thus forming a negative feedback loop that limits further activation of the signaling pathway. This discovery will advance understanding of how karrikins are perceived and how smoke-activated germination evolved. It will also aid identification of the elusive KL.

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