Analysis of the Effect of Phacoemulsification and Intraocular Lens Implantation Combined With Trabeculectomy on Cataract and Its Influence on Corneal Endothelium

Overview

Journal Front Surg

Specialty General Surgery

Date 2022 Mar 7

PMID 35252341

Authors

Bin Wang

Liqin Tang

Affiliations

Soon will be listed here.

Abstract

Objective: This study aimed to discuss the effect of phacoemulsification and intraocular lens implantation (PHACO + IOL) combined with trabeculectomy (TRAB) on cataracts and its influence on the corneal endothelium.

Methods: We selected 120 cataract patients admitted to our hospital from January 2018 to January 2021. According to different surgical methods, they were divided into the control group and the observation group. The observation group was treated with PHACO + IOL combined with TRAB, the control group only received PHACO. The clinical effect, ophthalmic-related parameters, corneal endothelium, complications, the satisfaction of the two groups were observed.

Results: The total effective rate and total satisfaction rate of the observation group were significantly higher than the control group ( < 0.05). One month after the operation, the vision and central anterior chamber depth of the observation group were higher than those of the control group, and intraocular pressure (IOP) was lower than that of the control group ( < 0.05). One month after the operation, the corneal endothelial cell area and cell density in the observation group were not significantly different from those before operation ( > 0.05). There was no significant difference in the total incidence of complications between the two groups ( > 0.05).

Conclusion: This study concluded that PHACO + IOL combined with TRAB has a good curative effect in the treatment of cataracts, which can improve the patients' vision and IOP, keep the functional integrity of corneal endothelial cells, and does not increase the occurrence of complications, the patients' satisfaction is high.

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References

Rao A, Padhy D, Das G, Sarangi S . Viscoless Manual Small Incision Cataract Surgery with Trabeculectomy. Semin Ophthalmol. 2017; 33(4):552-559. DOI: 10.1080/08820538.2017.1339092. View

Tan S, Chen X, Cui C, Hou Y, Li W, You H . Biodegradation of saline phenolic wastewater in a biological contact oxidation reactor with immobilized cells of Oceanimonas sp. Biotechnol Lett. 2016; 39(1):91-96. DOI: 10.1007/s10529-016-2226-9. View

Sangwan V, Gupta S, Das S . Cataract surgery in ocular surface diseases: clinical challenges and outcomes. Curr Opin Ophthalmol. 2017; 29(1):81-87. DOI: 10.1097/ICU.0000000000000441. View

Anbar M, Ammar H . Effect of different incision sites of phacoemulsification on trabeculectomy bleb function: prospective case-control study. BMC Ophthalmol. 2017; 17(1):103. PMC: 5485683. DOI: 10.1186/s12886-017-0500-9. View

Choi S, Jeon H, Hyon J, Oh Y, Wee W, Chung T . Recovery of Corneal Endothelial Cells from Periphery after Injury. PLoS One. 2015; 10(9):e0138076. PMC: 4574742. DOI: 10.1371/journal.pone.0138076. View

Fukuoka H, Afshari N . The impact of age-related cataract on measures of frailty in an aging global population. Curr Opin Ophthalmol. 2016; 28(1):93-97. DOI: 10.1097/ICU.0000000000000338. View

Qian Z, Huang J, Song B, Wei L, Fu L, Austin M . Cataract Surgery (Phacoemulsification with Intraocular Lens Implantation) Combined with Endoscopic Goniosynechialysis for Advanced Primary Angle-Closure Glaucoma. Ophthalmol Glaucoma. 2020; 4(4):365-372. DOI: 10.1016/j.ogla.2020.11.003. View

Avetisov K, Ivanov M, Yusef Y, Yusef S, Aslamazova A, Fokina N . [Morphological and clinical aspects of anterior capsulotomy in femtosecond laser-assisted cataract surgery]. Vestn Oftalmol. 2017; 133(4):83-88. DOI: 10.17116/oftalma2017133483-88. View

Agrawal S, Fledderjohann J, Ghosh S . Risk factors for self-reported cataract symptoms, diagnosis, and surgery uptake among older adults in India: Findings from the WHO SAGE data. Glob Public Health. 2020; 16(11):1771-1785. DOI: 10.1080/17441692.2020.1836246. View

10.

Foster G, Allen Q, Ayres B, Devgan U, Hoffman R, Khandelwal S . Phacoemulsification of the rock-hard dense nuclear cataract: Options and recommendations. J Cataract Refract Surg. 2018; 44(7):905-916. DOI: 10.1016/j.jcrs.2018.03.038. View

11.

Cairns J . Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol. 1968; 66(4):673-9. View

12.

Hansapinyo L, Choy B, Lai J, Tham C . Phacoemulsification Versus Phacotrabeculectomy in Primary Angle-closure Glaucoma With Cataract: Long-Term Clinical Outcomes. J Glaucoma. 2019; 29(1):15-23. DOI: 10.1097/IJG.0000000000001397. View

13.

Sarkisian Jr S, Radcliffe N, Harasymowycz P, Vold S, Patrianakos T, Zhang A . Visual outcomes of combined cataract surgery and minimally invasive glaucoma surgery. J Cataract Refract Surg. 2020; 46(10):1422-1432. DOI: 10.1097/j.jcrs.0000000000000317. View

14.

Maehara S, Matsumoto N, Takiyama N, Itoh Y, Kitamura Y, Yamashita K . Surgical removal of cataract in an Asiatic black bear (Ursus thibetanus) by phacoemulsification and aspiration. J Vet Med Sci. 2020; 82(6):740-744. PMC: 7324814. DOI: 10.1292/jvms.19-0639. View

15.

Evans J, Mwangi N, Burn H, Ramke J . Equity was rarely considered in Cochrane Eyes and Vision systematic reviews and primary studies on cataract. J Clin Epidemiol. 2020; 125:57-63. DOI: 10.1016/j.jclinepi.2020.04.024. View

16.

Nystrom A, Almarzouki N, Magnusson G, Zetterberg M . Phacoemulsification and primary implantation with bag-in-the-lens intraocular lens in children with unilateral and bilateral cataract. Acta Ophthalmol. 2018; 96(4):364-370. DOI: 10.1111/aos.13626. View

17.

Wang Y, Liang Z, Zhang Y, Hennein L, Han Y, Wu H . Efficacy and safety of phacoemulsification plus goniosynechialysis and trabectome in patients with primary angle-closure glaucoma. Sci Rep. 2021; 11(1):13921. PMC: 8260581. DOI: 10.1038/s41598-021-92972-9. View

18.

Kozera M, Konopinska J, Mariak Z, Rekas M . Effectiveness of iStent Trabecular Microbypass System Combined with Phacoemulsification versus Phacoemulsification Alone in Patients with Glaucoma and Cataract Depending on the Initial Intraocular Pressure. Ophthalmic Res. 2020; 64(2):327-336. DOI: 10.1159/000511456. View

19.

Frolov M, Frolov A, Kazakova K . [Combination treatment for cataract and glaucoma]. Vestn Oftalmol. 2017; 133(4):42-46. DOI: 10.17116/oftalma2017133442-46. View

20.

Han X, Fan Q, Hua Z, Qiu X, Qian D, Yang J . Analysis of corneal astigmatism and aberration in chinese congenital cataract and developmental cataract patients before cataract surgery. BMC Ophthalmol. 2021; 21(1):34. PMC: 7805192. DOI: 10.1186/s12886-020-01794-2. View