Middle Ear Surgeries for Chronic Otitis Media Improve Cognitive Functions and Quality of Life of Age-Related Hearing Loss Patients

Overview

Journal Front Neurosci

Date 2022 Mar 7

PMID 35250444

Authors

Juanjuan Gao

Junyan Chen

Jia Xu

Sichao Liang

Haijin Yi

Affiliations

Soon will be listed here.

Abstract

Age-related hearing loss (ARHL) may limit communication, which is closely associated with cognitive decline of the elderly and negatively affects their quality of life. In ARHL patients who suffer chronic otitis media (COM), hearing impairment may worsen and negatively affect the cognition and quality of life. It is currently unknown whether restoration of the conductive hearing in the mixed hearing loss through middle ear surgeries can improve both the cognitive function and quality of life of the ARHL patients. Therefore, in the present study, the ARHL patients were followed up for 6 months after middle ear surgeries for COM, and both the cognitive functions and quality of life of the patients were assessed using Montreal Cognitive Assessment and Glasgow Benefit Inventory. It was found that both the cognitive functions and quality of life were improved 6 months after middle ear surgeries. In conclusion, hearing recovery after middle ear surgeries could improve cognitive functions and quality of life of ARHL patients with COM, and surgical intervention is, hence, recommended for COM.

Citing Articles

Conductive Hearing Loss Associates With Dementia, and Middle Ear Reconstruction Mitigates This Association: A Multinational Database Study.

Urdang Z, Jain A, Li M, Haupt T, Wilcox T, Chiffer R Otol Neurotol. 2024; 45(9):1078-1086.

PMID: 39167564 PMC: 11392634. DOI: 10.1097/MAO.0000000000004308.

References

Xie R . Transmission of auditory sensory information decreases in rate and temporal precision at the endbulb of Held synapse during age-related hearing loss. J Neurophysiol. 2016; 116(6):2695-2705. PMC: 5133313. DOI: 10.1152/jn.00472.2016. View

Fulton S, Lister J, Harrison Bush A, Edwards J, Andel R . Mechanisms of the Hearing-Cognition Relationship. Semin Hear. 2016; 36(3):140-9. PMC: 4906307. DOI: 10.1055/s-0035-1555117. View

Griffiths T, Lad M, Kumar S, Holmes E, McMurray B, Maguire E . How Can Hearing Loss Cause Dementia?. Neuron. 2020; 108(3):401-412. PMC: 7664986. DOI: 10.1016/j.neuron.2020.08.003. View

Qiu C, Fratiglioni L . Aging without Dementia is Achievable: Current Evidence from Epidemiological Research. J Alzheimers Dis. 2018; 62(3):933-942. PMC: 5870011. DOI: 10.3233/JAD-171037. View

Vartiainen E, Karjalainen S . Surgery in elderly patients with chronic otitis media. Arch Otolaryngol. 1985; 111(8):509-10. DOI: 10.1001/archotol.1985.00800100057006. View

Wang P, Chu C, Liang S, Tai C, Gliklich R . Validation assessment of the Chinese-version Chronic Ear Survey: a comparison between data from English and Chinese versions. Ann Otol Rhinol Laryngol. 2003; 112(1):85-90. DOI: 10.1177/000348940311200116. View

Peelle J, Troiani V, Grossman M, Wingfield A . Hearing loss in older adults affects neural systems supporting speech comprehension. J Neurosci. 2011; 31(35):12638-43. PMC: 3175595. DOI: 10.1523/JNEUROSCI.2559-11.2011. View

Fortunato S, Forli F, Guglielmi V, De Corso E, Paludetti G, Berrettini S . A review of new insights on the association between hearing loss and cognitive decline in ageing. Acta Otorhinolaryngol Ital. 2016; 36(3):155-66. PMC: 4977003. DOI: 10.14639/0392-100X-993. View

Uchida Y, Sugiura S, Nishita Y, Saji N, Sone M, Ueda H . Age-related hearing loss and cognitive decline - The potential mechanisms linking the two. Auris Nasus Larynx. 2018; 46(1):1-9. DOI: 10.1016/j.anl.2018.08.010. View

10.

Mamo S, Reed N, Sharrett A, Albert M, Coresh J, Mosley T . Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study. Am J Audiol. 2019; 28(4):1006-1014. PMC: 7210433. DOI: 10.1044/2019_AJA-19-00043. View

11.

Nguyen M, Bonnefoy M, Adrait A, Gueugnon M, Petitot C, Collet L . Efficacy of Hearing Aids on the Cognitive Status of Patients with Alzheimer's Disease and Hearing Loss: A Multicenter Controlled Randomized Trial. J Alzheimers Dis. 2017; 58(1):123-137. DOI: 10.3233/JAD-160793. View

12.

Mulrow C, Aguilar C, Endicott J, Tuley M, Velez R, Charlip W . Quality-of-life changes and hearing impairment. A randomized trial. Ann Intern Med. 1990; 113(3):188-94. DOI: 10.7326/0003-4819-113-3-188. View

13.

Livingston G, Sommerlad A, Orgeta V, Costafreda S, Huntley J, Ames D . Dementia prevention, intervention, and care. Lancet. 2017; 390(10113):2673-2734. DOI: 10.1016/S0140-6736(17)31363-6. View

14.

Haggstrom J, Hederstierna C, Rosenhall U, Ostberg P, Idrizbegovic E . Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia. Audiol Neurootol. 2020; 25(5):276-282. DOI: 10.1159/000506621. View

15.

Hsiao Y, Chang C, Gean P . Impact of social relationships on Alzheimer's memory impairment: mechanistic studies. J Biomed Sci. 2018; 25(1):3. PMC: 5764000. DOI: 10.1186/s12929-018-0404-x. View

16.

Fischer M, Cruickshanks K, Wiley T, Klein B, Klein R, Tweed T . Determinants of hearing aid acquisition in older adults. Am J Public Health. 2011; 101(8):1449-55. PMC: 3134488. DOI: 10.2105/AJPH.2010.300078. View

17.

Kuiper J, Zuidersma M, Oude Voshaar R, Zuidema S, van den Heuvel E, Stolk R . Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies. Ageing Res Rev. 2015; 22:39-57. DOI: 10.1016/j.arr.2015.04.006. View

18.

Wayne R, Johnsrude I . A review of causal mechanisms underlying the link between age-related hearing loss and cognitive decline. Ageing Res Rev. 2015; 23(Pt B):154-66. DOI: 10.1016/j.arr.2015.06.002. View

19.

Yang R, Zhang Y, Han W, Li Y, Li S, Ke J . Measuring health-related quality of life in chronic otitis media in a Chinese population: cultural adaption and validation of the Zurich Chronic Middle Ear Inventory (ZCMEI-21-Chn). Health Qual Life Outcomes. 2020; 18(1):218. PMC: 7346638. DOI: 10.1186/s12955-020-01461-6. View

20.

Stahl S . Does treating hearing loss prevent or slow the progress of dementia? Hearing is not all in the ears, but who's listening?. CNS Spectr. 2017; 22(3):247-250. DOI: 10.1017/S1092852917000268. View