Fast and Accurate Deformable Contour Propagation for Intra-fraction Adaptive Magnetic Resonance-guided Prostate Radiotherapy

Overview

Journal Phys Imaging Radiat Oncol

Specialty Oncology

Date 2022 Mar 4

PMID 35243033

Authors

Thomas Willigenburg

Cornel Zachiu

Jan J W Lagendijk

Jochem R N van der Voort van Zyp

Hans C J de Boer

Bas W Raaymakers

Affiliations

Soon will be listed here.

Abstract

To facilitate full intra-fraction adaptive MR-guided radiotherapy, accurate contour propagation is needed. We aimed to assess the clinical usability of intra-fraction propagated contours by a deformable image registration algorithm in ten prostate cancer patients. Two observers judged the contours on need for manual adaptation and feasibility of adapting contours within 3 min. CTV and bladder contours needed none or only minor editing in most cases (≥ 97%), whereas rectum contours needed more extensive editing in 12-23%. Nevertheless, adaptation times were < 3 min for ≥ 93% of the cases. This paves the way for exploring adaptive workflows using intra-fraction deformable contour propagation.

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