Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management

Overview

Journal Dig Dis Sci

Specialty Gastroenterology

Date 2022 Mar 1

PMID 35230577

Authors

Edward Young

Hamish Philpott

Affiliations

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Abstract

Eosinophilic esophagitis (EoE) is a leading cause of food bolus impaction in children and adults. The mechanism of dysphagia in EoE, particularly non-obstructive dysphagia, remains incompletely understood. While fibrostenotic processes appear to be critical in the development of dysphagia, somatosensory dysfunction and dysmotility also contribute. This review considers potential mechanisms of dysphagia and evaluates the utility of current and future treatment strategies in this context.

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