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Hemiballismus Secondary to Metastatic Lung Cancer: A Case Report

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Journal Cureus
Date 2022 Feb 28
PMID 35223238
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Abstract

Hemiballismus is an unusual complication of brain metastasis of lung cancer. A 62-year-old woman suddenly presented with an acute movement disorder characterized by irregular, involuntary, and large-amplitude movements of the left half of her body. Brain magnetic resonance imaging (MRI) revealed metastasis in the right thalamic region. A whole-body CT scan revealed a lung tumor, while a biopsy showed small cell lung carcinoma. Vascular lesions that affect the basal ganglia, particularly the subthalamic nucleus, are the most common cause of hemiballismus. Hemiballismus is generally treated with antipsychotics such as tetrabenazine and haloperidol, but the primary treatment is the causal one. This was demonstrated in our patient since, after completion of the radio-chemotherapy sessions, the hemiballismus gradually decreased.

References
1.
CARPENTER M . Ballism associated with partial destruction of the subthalamic nucleus of luys. Neurology. 1955; 5(7):479-89. DOI: 10.1212/wnl.5.7.479. View

2.
Adali N, Kissani N . [Vascular hemiballismus due to extraluysian lesions]. Rev Neurol (Paris). 2008; 165(10):831-5. DOI: 10.1016/j.neurol.2008.10.017. View

3.
Kenney C, Jankovic J . Tetrabenazine in the treatment of hyperkinetic movement disorders. Expert Rev Neurother. 2006; 6(1):7-17. DOI: 10.1586/14737175.6.1.7. View

4.
WHITTIER J . Ballism and the subthalamic nucleus hypothalamicus; corpus luysi) review of the literature and study of 30 cases. Arch Neurol Psychiatry. 1947; 58(6):672-92. DOI: 10.1001/archneurpsyc.1947.02300350022002. View

5.
Wang G, Xu J, Qi Y, Xiu J, Li R, Han M . Distribution Of Brain Metastasis From Lung Cancer. Cancer Manag Res. 2019; 11:9331-9338. PMC: 6830371. DOI: 10.2147/CMAR.S222920. View