Infection in Patients with Psychiatric Disorders from Western Romania

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2022 Feb 25

PMID 35208532

Authors

Sebastian Grada

Alin Gabriel Mihu

Cristina Petrescu

Oana Suciu

Iosif Marincu

Maria Alina Lupu

Tudor Rares Olariu

Affiliations

Soon will be listed here.

Abstract

: High rates of infection with were found in psychiatric patients globally. In this study, we assessed for the first time the prevalence of infection in psychiatric patients and healthy individuals with no known psychiatric disorders in Western Romania. : The presence of specific IgG anti- antibodies was evaluated in 308 psychiatric patients and 296 control subjects using a chemiluminescence assay. : Overall, the seroprevalence of IgG antibodies was higher in psychiatric patients (67.86%; 209/308), compared with the control group (54.05%; 160/296) ( < 0.001). Our results revealed a significantly higher prevalence of antibodies among patients with schizophrenia (69.77%), organic (personality and behaviour) disorders (76.74%), and mental disorders concerning alcohol abuse (84.62%), compared with the control group ( = 0.009, = 0.005, = 0.043, respectively). : This study provides new and important information on the seroprevalence of in Romanian psychiatric patients and may serve for further scientific research regarding the status of infection in patients with psychiatric disorders.

Citing Articles

Seroprevalence and Associated Risk Factors of in Patients Diagnosed with Schizophrenia: A Case-Control Cross Sectional Study.

Grada S, Mihu A, Oatis D, Marc C, Chicea L, Petrescu C Biomedicines. 2024; 12(5).

PMID: 38790960 PMC: 11117935. DOI: 10.3390/biomedicines12050998.

A comprehensive assessment of toxoplasmosis and its dormant impact on psychotic disorders (Review).

Mares A, Varlam C, Iliuta F, Lacau R, Manea M Biomed Rep. 2024; 20(6):86.

PMID: 38665421 PMC: 11040222. DOI: 10.3892/br.2024.1774.

Prevalence of IgG Antibodies and Associated Risk Factors in Psychiatric Patients from Western Romania: A Cross-Sectional Study.

Grada S, Mihu A, Oatis D, Susan M, Lupu M, Olariu T Microorganisms. 2024; 12(1).

PMID: 38257998 PMC: 10820121. DOI: 10.3390/microorganisms12010172.

Infection in Patients with Cardiovascular Diseases from Western Romania: A Case-Control Study.

Dragomir A, Lupu M, Lighezan R, Paduraru A, Olariu T Life (Basel). 2023; 13(7).

PMID: 37511950 PMC: 10382031. DOI: 10.3390/life13071575.

Global seroprevalence of infection among patients with mental and neurological disorders: A systematic review and meta-analysis.

Bisetegn H, Debash H, Ebrahim H, Mahmood N, Gedefie A, Tilahun M Health Sci Rep. 2023; 6(6):e1319.

PMID: 37287705 PMC: 10242185. DOI: 10.1002/hsr2.1319.

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