Association Between Ocular Parameters and Intraocular Pressure Elevation During Femtosecond Laser-Assisted Cataract Surgery in Open-Angle Glaucoma and Nonglaucoma Individuals

Overview

Journal J Pers Med

Date 2022 Feb 25

PMID 35207745

Authors

Ya-Hui Wang

Yi-Zhen He

Ming-Hsuan Chiang

Chia-Yi Lee

Chien-Liang Wu

Affiliations

Soon will be listed here.

Abstract

In this study, we evaluate the association between biometrics and intraocular pressure (IOP) during femtosecond laser-assisted cataract surgery (FLACS) in normal patients and those with open-angle glaucoma (OAG). A retrospective cross-sectional study was conducted. A total of 103 patients who had received elective FLACS were enrolled, and those with OAG who received FLACS were further divided into a subgroup. The perioperative IOP of FLACS was measured before, during, and after the suction procedure. Demographic data and preoperative biometrics were collected from the medical records. The generalized linear model was applied to yield the adjusted odds ratio (aOR) and corresponding 95% confidence interval (CI) of each biometric for the IOP elevation in the whole group and the OAG subgroup. The mean preoperative IOP was 20.96 ± 4.79 mmHg, which rose to 55.37 ± 11.58 mmHg during suction, and decreased to 23.75 ± 6.42 mmHg after suction; the IOP both during and after suction was significantly higher than the presuction IOP (both < 0.001). The mean IOP elevation was 34.41 ± 9.70 mmHg in the whole study population, and the difference in IOP elevation between OAG and nonglaucoma subgroups was not significant ( = 0.159). In the whole group, the presuction IOP, postdilated pupil size (PPS), and central corneal thickness (CCT) were positively corrected to higher IOP elevation (all < 0.05), while axial length (AL) was negatively related to IOP elevation (aOR: 0.020, 95% CI: 0.008-0.699, = 0.042). For the OAG subgroup, the longer AL was more significantly correlated to lower IOP elevation compared to those without glaucoma (aOR: 0.231, 95% CI: 0.106-0.502, = 0.006). In conclusion, presuction IOP, PPS, and CCT are related to higher IOP during FLAC, while the AL is negatively correlated to the IOP elevation in FLACS, especially for patients with OAG. Reviewing these parameters before FLACS may enable physicians to find patients who are at risk of IOP elevation.

References

Ye Z, Li Z, He S . A Meta-Analysis Comparing Postoperative Complications and Outcomes of Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification for Cataract. J Ophthalmol. 2017; 2017:3849152. PMC: 5429954. DOI: 10.1155/2017/3849152. View

Mariacher S, Laubichler P, Mariacher M, Wendelstein J, Fischinger I, Bolz M . Impact of baseline IOP, vacuum, and different docking mechanisms, and their interaction on IOP rise in femtosecond laser-assisted refractive and cataract surgery. J Cataract Refract Surg. 2019; 45(12):1818-1825. DOI: 10.1016/j.jcrs.2019.07.020. View

Talamo J, Gooding P, Angeley D, Culbertson W, Schuele G, Andersen D . Optical patient interface in femtosecond laser-assisted cataract surgery: contact corneal applanation versus liquid immersion. J Cataract Refract Surg. 2013; 39(4):501-10. DOI: 10.1016/j.jcrs.2013.01.021. View

Schultz T, Conrad-Hengerer I, Hengerer F, Dick H . Intraocular pressure variation during femtosecond laser-assisted cataract surgery using a fluid-filled interface. J Cataract Refract Surg. 2012; 39(1):22-27. DOI: 10.1016/j.jcrs.2012.10.038. View

Abouzeid H, Ferrini W . Femtosecond-laser assisted cataract surgery: a review. Acta Ophthalmol. 2014; 92(7):597-603. DOI: 10.1111/aos.12416. View

Sperl P, Strohmaier C, Kraker H, Motloch K, Lenzhofer M, Moussa S . Intraocular Pressure Course During the Femtosecond Laser-Assisted Cataract Surgery in Porcine Cadaver Eyes. Invest Ophthalmol Vis Sci. 2017; 58(14):6457-6461. DOI: 10.1167/iovs.17-21948. View

Kohnen T . Interface for femtosecond laser-assisted lens surgery. J Cataract Refract Surg. 2013; 39(4):491-2. DOI: 10.1016/j.jcrs.2013.02.033. View

Kerr N, Abell R, Vote B, Toh T . Intraocular pressure during femtosecond laser pretreatment of cataract. J Cataract Refract Surg. 2013; 39(3):339-42. DOI: 10.1016/j.jcrs.2012.12.008. View

Baig N, Cheng G, Lam J, Jhanji V, Chong K, Woo V . Intraocular pressure profiles during femtosecond laser-assisted cataract surgery. J Cataract Refract Surg. 2014; 40(11):1784-9. DOI: 10.1016/j.jcrs.2014.04.026. View

10.

Yang Y, Ng T, Wang L, Wu N, Xiao M, Sun X . Association of 24-Hour Intraocular Pressure Fluctuation With Corneal Hysteresis and Axial Length in Untreated Chinese Primary Open-Angle Glaucoma Patients. Transl Vis Sci Technol. 2020; 9(12):25. PMC: 7683862. DOI: 10.1167/tvst.9.12.25. View

11.

Foster P, Broadway D, Garway-Heath D, Yip J, Luben R, Hayat S . Intraocular pressure and corneal biomechanics in an adult British population: the EPIC-Norfolk eye study. Invest Ophthalmol Vis Sci. 2011; 52(11):8179-85. DOI: 10.1167/iovs.11-7853. View

12.

Mariacher S, Laubichler P, Wendelstein J, Mariacher M, Bolz M . Preoperative intraocular pressure as a strong predictive factor for intraocular pressure rise during vacuum application in femtosecond laser-assisted cataract surgery. Acta Ophthalmol. 2019; 97(8):e1123-e1129. DOI: 10.1111/aos.14149. View

13.

Abell R, Kerr N, Howie A, Mustaffa Kamal M, Allen P, Vote B . Effect of femtosecond laser-assisted cataract surgery on the corneal endothelium. J Cataract Refract Surg. 2014; 40(11):1777-83. DOI: 10.1016/j.jcrs.2014.05.031. View

14.

Bissen-Miyajima H, Suzuki S, Ohashi Y, Minami K . Experimental observation of intraocular pressure changes during microkeratome suctioning in laser in situ keratomileusis. J Cataract Refract Surg. 2005; 31(3):590-4. DOI: 10.1016/j.jcrs.2004.06.085. View

15.

Gaspar R, Abegao Pinto L, Sousa D . Corneal properties and glaucoma: a review of the literature and meta-analysis. Arq Bras Oftalmol. 2017; 80(3):202-206. DOI: 10.5935/0004-2749.20170050. View

16.

Ebner M, Mariacher S, Januschowski K, Boden K, Seuthe A, Szurman P . Comparison of intraocular pressure during the application of a liquid patient interface (FEMTO LDV Z8) for femtosecond laser-assisted cataract surgery using two different vacuum levels. Br J Ophthalmol. 2017; 101(8):1138-1142. DOI: 10.1136/bjophthalmol-2016-309890. View

17.

Kohlhaas M, Boehm A, Spoerl E, Pursten A, Grein H, Pillunat L . Effect of central corneal thickness, corneal curvature, and axial length on applanation tonometry. Arch Ophthalmol. 2006; 124(4):471-6. DOI: 10.1001/archopht.124.4.471. View

18.

Roberts H, Day A, OBrart D . Femtosecond laser-assisted cataract surgery: A review. Eur J Ophthalmol. 2019; 30(3):417-429. DOI: 10.1177/1120672119893291. View

19.

Doughty M, Zaman M . Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 2000; 44(5):367-408. DOI: 10.1016/s0039-6257(00)00110-7. View

20.

Bikbov M, Gilmanshin T, Zainullin R, Kazakbaeva G, Arslangareeva I, Panda-Jonas S . Prevalence and associated factors of glaucoma in the Russian Ural Eye and Medical Study. Sci Rep. 2020; 10(1):20307. PMC: 7679388. DOI: 10.1038/s41598-020-77344-z. View