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Grapevine Wastes: A Rich Source of Antioxidants and Other Biologically Active Compounds

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Date 2022 Feb 25
PMID 35204275
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Abstract

Wine production is one of the most critical agro-industrial sectors worldwide, generating large amounts of waste with negative environmental impacts, but also with high economic value and several potential applications. From wine shoots to grape pomace or seeds, all of the wastes are rich sources of bioactive compounds with beneficial effects for human health, with these compounds being raw materials for other industries such as the pharmaceutical, cosmetic or food industries. Furthermore, these compounds present health benefits such as being antioxidants, supporting the immune system, anti-tumoral, or preventing cardiovascular and neural diseases. The present work aims to be a critical discussion of the extraction methods used for bioactive compounds from grapevine waste and their beneficial effects on human health.

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References
1.
Troilo M, Difonzo G, Paradiso V, Summo C, Caponio F . Bioactive Compounds from Vine Shoots, Grape Stalks, and Wine Lees: Their Potential Use in Agro-Food Chains. Foods. 2021; 10(2). PMC: 7915647. DOI: 10.3390/foods10020342. View

2.
Virgili F, Marino M . Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activity. Free Radic Biol Med. 2008; 45(9):1205-16. DOI: 10.1016/j.freeradbiomed.2008.08.001. View

3.
Ferzli G, Patel M, Phrsai N, Brody N . Reduction of facial redness with resveratrol added to topical product containing green tea polyphenols and caffeine. J Drugs Dermatol. 2013; 12(7):770-4. View

4.
Malinowska M, Billet K, Drouet S, Munsch T, Unlubayir M, Tungmunnithum D . Grape Cane Extracts as Multifunctional Rejuvenating Cosmetic Ingredient: Evaluation of Sirtuin Activity, Tyrosinase Inhibition and Bioavailability Potential. Molecules. 2020; 25(9). PMC: 7249022. DOI: 10.3390/molecules25092203. View

5.
Oliveira W, Biasoto A, Marques V, Dos Santos I, Magalhaes K, Correa L . Phenolics from Winemaking By-Products Better Decrease VLDL-Cholesterol and Triacylglycerol Levels than Those of Red Wine in Wistar Rats. J Food Sci. 2017; 82(10):2432-2437. DOI: 10.1111/1750-3841.13841. View