Persistence and Dissemination Capacities of a -Harboring IncX-3 Plasmid in Isolated from an Urban River in Montpellier, France

Overview

Journal Antibiotics (Basel)

Specialty Pharmacology

Date 2022 Feb 25

PMID 35203799

Authors

Florence Hammer-Dedet

Fabien Aujoulat

Estelle Jumas-Bilak

Patricia Licznar-Fajardo

Affiliations

Soon will be listed here.

Abstract

To investigate the capacities of persistence and dissemination of within and in aquatic environment, we characterized (sequence type 636) strains B26 and B28 isolated one month apart from the same urban river in Montpellier, France. The two isolates carried a pTsB26 plasmid, which sized 45,495 Kb, harbored gene and belonged to IncX-3 incompatibility group. pTsB26 was conjugative in vitro at high frequency, it was highly stable after 400 generations and it exerted no fitness cost on its host. harboring plasmids are widely dispersed in all around the world, with no lineage specialization. The genomic comparison between B26 and B28 stated that the two isolates probably originated from the same clone, suggesting the persistence of pTsB26 in an host in aquatic environment.

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