Development of an Embryo Transfer Model to Study Uterine Contributions to Pregnancy in Mice

Overview

Journal Reprod Fertil

Specialty Reproductive Medicine

Date 2022 Feb 24

PMID 35198982

Authors

Meaghan J Griffiths

Lauren R Alesi

Amy L Winship

Karla J Hutt

Affiliations

Soon will be listed here.

Abstract

Lay Summary: Many pregnancy complications occur because of problems in the womb (uterus), specifically the womb lining. There is a close relationship between the hormone function of the ovaries and the uterus and distinguishing between the way they both impact pregnancy success is difficult in existing studies using animals. Here, we developed a new animal model to utilize in addressing these gaps in our understanding of pregnancy.

Citing Articles

Radiotherapy exposure directly damages the uterus and causes pregnancy loss.

Griffiths M, Marshall S, Cousins F, Alesi L, Higgins J, Giridharan S JCI Insight. 2023; 8(6).

PMID: 36946464 PMC: 10070119. DOI: 10.1172/jci.insight.163704.

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