An Immunological Study of a Pb-thionein Like Protein in Rat Liver

Overview

Journal Biochem Biophys Res Commun

Publisher Elsevier

Specialty Biochemistry

Date 1986 Apr 29

PMID 3518716

Citations 2

Authors

H IKEBUCHI

R Teshima

K Suzuki

J Sawada

T Terao

Y Yamane

Affiliations

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Abstract

Administration of a sublethal dose of lead acetate to rats induced the simultaneous synthesis of a Pb-thionein like protein (Pb-BP) and Zn-thionein in the liver. To determine of the Pb-BP is a species of metallothionein, immunological properties of this protein were investigated. The results indicate that the Pb-BP is cross-reactive with the antibody against rat Zn-thionein II, strongly suggesting that the Pb-BP is a metallothionein.

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