Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease

Overview

Journal Front Cardiovasc Med

Specialty Cardiology & Vascular Diseases

Date 2022 Feb 21

PMID 35187117

Authors

Srisakul Chaichuum

Shuo-Ju Chiang

Masao Daimon

Su-Chen Chang

Chih-Lin Chan

Chu-Ying Hsu

Hsiang-Ho Chen

Ching-Li Tseng

Affiliations

Soon will be listed here.

Abstract

Objective: Two-dimensional speckle tracking echocardiography (2D-STE) has been used as a diagnostic tool for coronary artery disease (CAD). However, whether vessel supplied myocardial strain and strain rate (SR) predict the severity of coronary artery stenosis in patients with CAD is unknown. This study aimed to investigate correlation of cardiac mechanical parameters in tissue speckle tracking measurements with coronary artery stenosis diagnosed by cardiac catheterization in patients with clinically diagnosed CAD.

Methods And Results: Among 59 patients analyzed, 170 vessels were evaluated by coronary angiography and the corresponding echocardiography to quantify left ventricular myocardial strain and SR. The average longitudinal strain and SR of the segmental myocardium supplied by each coronary artery were calculated to achieve vessel myocardium strain (VMS) and strain rate (VMSR). The VMS and VMSR at each of four severity levels of stenosis showed significant differences among groups ( = 0.016, and < 0.001, respectively). The strain and SR in vessels with very severe stenosis (≥75%, group IV; = 29), 13.9 ± 4.3, and 0.9 ± 0.3, respectively, were significantly smaller than those of vessels with mild stenosis ≤ 25%, group I; = 88, 16.9 ± 4.9, = 0.023, and 1.2 ± 0.3, = 0.001, respectively. The SR in vessels with moderate stenosis (26-49%, group II; = 37), 1.0 ± 0.2, was significantly smaller than that in vessels with mild stenosis vessels ( = 0.021). The lower VMS and VMSR, the higher possibility of severe coronary stenosis is. The VMS and VMSR lower than 13.9 ± 4.3 and 0.9 ± 0.3, respectively predicted the severe coronary stenosis. The VMS and VMSR higher than 16.9 ± 4.9 and 1.2 ± 0.3, respectively predicted mild or no coronary artery stenosis.

Conclusions: The actual stenosis rate in catheterization demonstrates that this technique was able to assess coronary artery condition. Thus, the application of a non-invasive method of 2D-STE to evaluate and simplify diagnosis of CAD is feasible.

Citing Articles

Resting segmental speckle tracking strain and strain rate in stable coronary artery disease and revascularized myocardial infarction.

Caglayan H, Kjonas D, Kornev M, Iqbal A, Jazbani M, Rosner A Int J Cardiovasc Imaging. 2024; 40(10):2077-2086.

PMID: 39179715 PMC: 11499336. DOI: 10.1007/s10554-024-03200-0.

Assessment of cardiac adverse events following COVID-19 vaccination by speckle tracking echocardiography.

Chaichuum S, Tseng C, Chang S, Chan C, Hsu C, Chiang E Sci Rep. 2024; 14(1):10849.

PMID: 38740940 PMC: 11091216. DOI: 10.1038/s41598-024-61641-y.

Predictive value of speckle tracking technique for coronary artery stenosis in patients with coronary heart disease.

Qin S, Cao X, Zhang R, Liu H Am J Transl Res. 2023; 15(9):5873-5881.

PMID: 37854206 PMC: 10579018.

Global and regional myocardial function assessment in symptomatic patients with chronic coronary syndrome using longitudinal strain and noninvasive myocardial work.

Lv H, Jiang Y, Tan X, Wang J, Liu Y Int J Cardiovasc Imaging. 2023; 39(12):2465-2474.

PMID: 37728801 DOI: 10.1007/s10554-023-02951-6.

Strain Rate Changes during Stress Echocardiography Are the Most Accurate Predictors of Significant Coronary Artery Disease in Patients with Previously Treated Acute Coronary Syndrome.

Shenouda R, Bytyci I, El Sharkawy E, Hisham N, Sobhy M, Henein M Diagnostics (Basel). 2023; 13(10).

PMID: 37238281 PMC: 10217636. DOI: 10.3390/diagnostics13101796.

References

Pislaru C, Abraham T, Belohlavek M . Strain and strain rate echocardiography. Curr Opin Cardiol. 2002; 17(5):443-54. DOI: 10.1097/00001573-200209000-00002. View

Castro P, Greenberg N, Drinko J, Garcia M, Thomas J . Potential pitfalls of strain rate imaging: angle dependency. Biomed Sci Instrum. 2000; 36:197-202. View

Miller T, Askew J, Anavekar N . Noninvasive Stress Testing for Coronary Artery Disease. Heart Fail Clin. 2015; 12(1):65-82. DOI: 10.1016/j.hfc.2015.08.006. View

Zhang Y, Gao Y, Wang L, Chen J, Shi X . The removal of wall components in Doppler ultrasound signals by using the empirical mode decomposition algorithm. IEEE Trans Biomed Eng. 2007; 54(9):1631-42. DOI: 10.1109/TBME.2007.891936. View

Dhooge J, HEIMDAL A, Jamal F, Kukulski T, Bijnens B, Rademakers F . Regional strain and strain rate measurements by cardiac ultrasound: principles, implementation and limitations. Eur J Echocardiogr. 2002; 1(3):154-70. DOI: 10.1053/euje.2000.0031. View

Greenberg N, Firstenberg M, Castro P, Main M, Travaglini A, Odabashian J . Doppler-derived myocardial systolic strain rate is a strong index of left ventricular contractility. Circulation. 2002; 105(1):99-105. DOI: 10.1161/hc0102.101396. View

Dove J, Jacobs A, Kennedy J, Kereiakes D, Kern M, Kuntz R . ACC/AHA guidelines for percutaneous coronary intervention (revision of the 1993 PTCA guidelines)-executive summary: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee to revise the.... Circulation. 2001; 103(24):3019-41. DOI: 10.1161/01.cir.103.24.3019. View

Singh M, Sethi A, Mishra A, Subrayappa N, Stapleton D, Pellikka P . Echocardiographic Imaging Challenges in Obesity: Guideline Recommendations and Limitations of Adjusting to Body Size. J Am Heart Assoc. 2020; 9(2):e014609. PMC: 7033836. DOI: 10.1161/JAHA.119.014609. View

Lang R, Badano L, Mor-Avi V, Afilalo J, Armstrong A, Ernande L . Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015; 28(1):1-39.e14. DOI: 10.1016/j.echo.2014.10.003. View

10.

Virani S, Alonso A, Aparicio H, Benjamin E, Bittencourt M, Callaway C . Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association. Circulation. 2021; 143(8):e254-e743. DOI: 10.1161/CIR.0000000000000950. View

11.

Reisner S, Lysyansky P, Agmon Y, Mutlak D, Lessick J, Friedman Z . Global longitudinal strain: a novel index of left ventricular systolic function. J Am Soc Echocardiogr. 2004; 17(6):630-3. DOI: 10.1016/j.echo.2004.02.011. View

12.

Sharp A, Tapp R, Thom S, Francis D, Hughes A, Stanton A . Tissue Doppler E/E' ratio is a powerful predictor of primary cardiac events in a hypertensive population: an ASCOT substudy. Eur Heart J. 2009; 31(6):747-52. DOI: 10.1093/eurheartj/ehp498. View

13.

Belohlavek M, Pislaru C, Bae R, Greenleaf J, Seward J . Real-time strain rate echocardiographic imaging: temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium. J Am Soc Echocardiogr. 2001; 14(5):360-9. DOI: 10.1067/mje.2001.110786. View

14.

Lacalzada J, de la Rosa A, Izquierdo M, Jimenez J, Iribarren J, Garcia-Gonzalez M . Left ventricular global longitudinal systolic strain predicts adverse remodeling and subsequent cardiac events in patients with acute myocardial infarction treated with primary percutaneous coronary intervention. Int J Cardiovasc Imaging. 2015; 31(3):575-84. DOI: 10.1007/s10554-015-0593-2. View

15.

Nagueh S, Smiseth O, Appleton C, Byrd 3rd B, Dokainish H, Edvardsen T . Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016; 29(4):277-314. DOI: 10.1016/j.echo.2016.01.011. View

16.

Finkelhor R, Moallem M, Bahler R . Characteristics and impact of obesity on the outpatient echocardiography laboratory. Am J Cardiol. 2006; 97(7):1082-4. DOI: 10.1016/j.amjcard.2005.10.052. View

17.

Cuspidi C, Rescaldani M, Sala C, Grassi G . Left-ventricular hypertrophy and obesity: a systematic review and meta-analysis of echocardiographic studies. J Hypertens. 2013; 32(1):16-25. DOI: 10.1097/HJH.0b013e328364fb58. View

18.

Weidemann F, Jamal F, Sutherland G, Claus P, Kowalski M, Hatle L . Myocardial function defined by strain rate and strain during alterations in inotropic states and heart rate. Am J Physiol Heart Circ Physiol. 2002; 283(2):H792-9. DOI: 10.1152/ajpheart.00025.2002. View

19.

Shalbaf A, Behnam H, Alizade-Sani Z, Shojaifard M . Automatic classification of left ventricular regional wall motion abnormalities in echocardiography images using nonrigid image registration. J Digit Imaging. 2013; 26(5):909-19. PMC: 3782595. DOI: 10.1007/s10278-012-9543-x. View

20.

Chatzizisis Y, Murthy V, Solomon S . Echocardiographic evaluation of coronary artery disease. Coron Artery Dis. 2013; 24(7):613-23. DOI: 10.1097/MCA.0000000000000028. View