Relationship Between Sleep Duration and Stroke History in Middle-Aged and Elderly in Guiyang: A Cross-Sectional Survey

Overview

Journal Neuropsychiatr Dis Treat

Publisher Dove Medical Press

Specialty Psychiatry

Date 2022 Feb 21

PMID 35185332

Authors

Li Liu

Jingyuan Yang

Junhua Wang

Meng Nie

Ziyun Wang

Han Guan

Jin Hu

Feng Hong

Affiliations

Soon will be listed here.

Abstract

Background: With over 2 million new cases annually, stroke is associated with the higher amount of disability-adjusted life-years lost than any other disease in China; however, the relationship between sleep time and stroke has not been concluded yet. Aim of this study was to analyze the relationship between sleep duration and stroke history in middle-aged and elderly people in Guiyang, China.

Methods: This study was a cross-sectional survey carried out in 40-99-years-old permanent residents of Guiyang. Yunyan, Wudang, and Baiyun districts and Xiuwen County were selected by stratified multilevel sampling for a face-to-face survey. Demographics, history of stroke, and self-reported sleep behavior data were collected, and multivariable logistic regression models were used to gradually adjust possible confounding factors.

Results: A total of 5065 participants were included, of them 126 (2.5%) had a history of stroke. Short sleep (<7 h) was observed in 11.0%, sufficient sleep (7-9 h) in 69.4%, and long sleep (>9 h) in 19.6%. Sleep duration and stroke prevalence showed a U-shaped distribution. When taking the sleep duration of 7-9 h as a reference, sleep duration >9 h was associated with stroke (all P < 0.05) in the univariable model (OR = 2.68, 95% CI: 1.83-3.93) and in the multivariable models 1 (OR = 2.35, 95% CI: 1.59-3.47), 2 (OR = 2.27, 95% CI: 1.53-3.37), 3 (OR = 2.25, 95% CI: 1.51-3.33), and 4 (OR = 2.11, 95% CI: 1.39-3.19). There were no significant differences between the <7 and 7-9 h groups (P > 0.05).

Conclusion: Thus, long sleep duration (>9 h) is independently associated with history of stroke in middle-aged and elderly people in Guiyang.

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References

Li L, Yang Y, Guan B, Chen Q, Wang A, Wang Y . Insomnia is associated with increased mortality in patients with first-ever stroke: a 6-year follow-up in a Chinese cohort study. Stroke Vasc Neurol. 2019; 3(4):197-202. PMC: 6312128. DOI: 10.1136/svn-2017-000136. View

Patel S, Malhotra A, Gottlieb D, White D, Hu F . Correlates of long sleep duration. Sleep. 2006; 29(7):881-9. PMC: 3500381. DOI: 10.1093/sleep/29.7.881. View

Lunardi Baccetto S, Lehmann C . Microcirculatory Changes in Experimental Models of Stroke and CNS-Injury Induced Immunodepression. Int J Mol Sci. 2019; 20(20). PMC: 6834192. DOI: 10.3390/ijms20205184. View

Abe T, Aoki T, Yata S, Okada M . Sleep duration is significantly associated with carotid artery atherosclerosis incidence in a Japanese population. Atherosclerosis. 2011; 217(2):509-13. DOI: 10.1016/j.atherosclerosis.2011.02.029. View

Ford E, Caspersen C . Sedentary behaviour and cardiovascular disease: a review of prospective studies. Int J Epidemiol. 2012; 41(5):1338-53. PMC: 4582407. DOI: 10.1093/ije/dys078. View

Debette S, Beiser A, DeCarli C, Au R, Himali J, Kelly-Hayes M . Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study. Stroke. 2010; 41(4):600-6. PMC: 2847685. DOI: 10.1161/STROKEAHA.109.570044. View

Ramos A, Dong C, Rundek T, Elkind M, Boden-Albala B, Sacco R . Sleep duration is associated with white matter hyperintensity volume in older adults: the Northern Manhattan Study. J Sleep Res. 2014; 23(5):524-30. PMC: 4177451. DOI: 10.1111/jsr.12177. View

Ji A, Lou H, Lou P, Xu C, Zhang P, Qiao C . Interactive effect of sleep duration and sleep quality on risk of stroke: An 8-year follow-up study in China. Sci Rep. 2020; 10(1):8690. PMC: 7250859. DOI: 10.1038/s41598-020-65611-y. View

Yaggi H, Concato J, Kernan W, Lichtman J, Brass L, Mohsenin V . Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med. 2005; 353(19):2034-41. DOI: 10.1056/NEJMoa043104. View

10.

Sacco R, Kasner S, Broderick J, Caplan L, Connors J, Culebras A . An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013; 44(7):2064-89. PMC: 11078537. DOI: 10.1161/STR.0b013e318296aeca. View

11.

Jiang B, Wang W, Chen H, Hong Z, Yang Q, Wu S . Incidence and trends of stroke and its subtypes in China: results from three large cities. Stroke. 2005; 37(1):63-8. DOI: 10.1161/01.STR.0000194955.34820.78. View

12.

Zhou L, Yu K, Yang L, Wang H, Xiao Y, Qiu G . Sleep duration, midday napping, and sleep quality and incident stroke: The Dongfeng-Tongji cohort. Neurology. 2019; 94(4):e345-e356. DOI: 10.1212/WNL.0000000000008739. View

13.

Yang L, Yang H, He M, Pan A, Li X, Min X . Longer Sleep Duration and Midday Napping Are Associated with a Higher Risk of CHD Incidence in Middle-Aged and Older Chinese: the Dongfeng-Tongji Cohort Study. Sleep. 2015; 39(3):645-52. PMC: 4763372. DOI: 10.5665/sleep.5544. View

14.

. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004; 363(9403):157-63. DOI: 10.1016/S0140-6736(03)15268-3. View

15.

Dowd J, Goldman N, Weinstein M . Sleep duration, sleep quality, and biomarkers of inflammation in a Taiwanese population. Ann Epidemiol. 2011; 21(11):799-806. PMC: 3204862. DOI: 10.1016/j.annepidem.2011.07.004. View

16.

De Baca T, Chayama K, Redline S, Slopen N, Matsushita F, Prather A . Sleep debt: the impact of weekday sleep deprivation on cardiovascular health in older women. Sleep. 2019; 42(10). PMC: 6783901. DOI: 10.1093/sleep/zsz149. View

17.

Meschia J, Bushnell C, Boden-Albala B, Braun L, Bravata D, Chaturvedi S . Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014; 45(12):3754-832. PMC: 5020564. DOI: 10.1161/STR.0000000000000046. View

18.

Hermann D, Bassetti C . Role of sleep-disordered breathing and sleep-wake disturbances for stroke and stroke recovery. Neurology. 2016; 87(13):1407-16. PMC: 5047039. DOI: 10.1212/WNL.0000000000003037. View

19.

Wang W, Jiang B, Sun H, Ru X, Sun D, Wang L . Prevalence, Incidence, and Mortality of Stroke in China: Results from a Nationwide Population-Based Survey of 480 687 Adults. Circulation. 2017; 135(8):759-771. DOI: 10.1161/CIRCULATIONAHA.116.025250. View

20.

Su H . Inflammation and genetic factors in stroke pathogenesis. Neuroimmunol Neuroinflamm. 2018; 4:260-262. PMC: 5828685. DOI: 10.20517/2347-8659.2017.22. View