Incidence of COVID-19 Infection in Hospital Workers from March 1, 2020 to May 31, 2021 Routinely Tested, Before and After Vaccination with BNT162B2

Overview

Journal Sci Rep

Specialty Science

Date 2022 Feb 16

PMID 35169127

Authors

Francesca Larese Filon

Francesca Rui

Federico Ronchese

Paola De Michieli

Corrado Negro

Affiliations

Soon will be listed here.

Abstract

To evaluate the incidence of COVID-19 infection in health care workers from the start of the COVID-19 pandemic in NE Italy, vaccination with BNT162b2. This was a retrospective cohort study. Healthcare workers were routinely tested for SARS-CoV-2 infection using real-time polymerase chain reaction tests in nasopharyngeal swabs. Logistic regression was used to calculate the incidence rate ratios (IRRs) of the factors associated with COVID-19. A total of 4251 workers were followed up, and the prevalence of COVID-19 was 13.6%. In March 2021 the incidence of infection was 4.88 and 103.55 cases for 100,000 person-days in vaccinated and non-vaccinated workers, respectively, with an adjusted IRRs of 0.05 (95% CI 0.02-0.08). Our study evaluated the monthly incidence in health care workers in Trieste hospitals before and after vaccination, finding an estimated vaccine effectiveness of 95% in health care workers routinely tested.

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