Invasive Mole Resulting in Uterine Rupture: A Case Report

Overview

Journal Front Surg

Specialty General Surgery

Date 2022 Feb 14

PMID 35155552

Authors

Anshan Wu

Qiong Zhu

Chang Tan

Long Chen

Yin Tao

Affiliations

Soon will be listed here.

Abstract

Uterine surgery is a common predisposing factor for uterine rupture, while an invasive mole that leads to uterine rupture is a rare clinical occurrence. Here, we report a case of a 31-year-old childless woman who underwent abortion after 53 days of pregnancy. She still experienced abdominal pain and scanty vaginal bleeding after the abortion. Her levels of human chorionic gonadotropin (HCG) were high, while ultrasound and MRI results revealed an enlarged uterus and a mass in the myometrium. During preparation for treatment, the gynecologist ruptured the uterus of the patient, leaving her shocked. Eventually the patient's uterus was removed the uterus and pathologically diagnosed as result is the an invasive mole.

Citing Articles

Papillary puncture is still a routine puncture path.

Luo Y, Chen M, Zhong F, Su H, Ou X, Lei M World J Urol. 2022; 40(5):1255-1256.

PMID: 35253095 DOI: 10.1007/s00345-022-03961-0.

References

Allen S, Lim A, Seckl M, Blunt D, Mitchell A . Radiology of gestational trophoblastic neoplasia. Clin Radiol. 2006; 61(4):301-13. DOI: 10.1016/j.crad.2005.12.003. View

Lee H, Kim Y . A case report of pelviscopic resection of invasive hydatidiform mole. Medicine (Baltimore). 2019; 98(41):e17565. PMC: 6799454. DOI: 10.1097/MD.0000000000017565. View

Chiofalo B, Palmara V, Lagana A, Triolo O, Vitale S, Conway F . Fertility Sparing Strategies in Patients Affected by Placental Site Trophoblastic Tumor. Curr Treat Options Oncol. 2017; 18(10):58. DOI: 10.1007/s11864-017-0502-0. View

Lurain J . Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. Am J Obstet Gynecol. 2010; 203(6):531-9. DOI: 10.1016/j.ajog.2010.06.073. View

Wang Q, Fu J, Hu L, Fang F, Xie L, Chen H . Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia. Cochrane Database Syst Rev. 2017; 9:CD007289. PMC: 6483742. DOI: 10.1002/14651858.CD007289.pub3. View

Seckl M, Sebire N, Berkowitz R . Gestational trophoblastic disease. Lancet. 2010; 376(9742):717-29. DOI: 10.1016/S0140-6736(10)60280-2. View

Abu-Rustum N, Yashar C, Bean S, Bradley K, Campos S, Chon H . Gestational Trophoblastic Neoplasia, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019; 17(11):1374-1391. DOI: 10.6004/jnccn.2019.0053. View

Wang X, Yang J, Li J, Zhao J, Ren T, Feng F . Fertility-sparing uterine lesion resection for young women with gestational trophoblastic neoplasias: single institution experience. Oncotarget. 2017; 8(26):43368-43375. PMC: 5522152. DOI: 10.18632/oncotarget.14727. View

Zhao P, Lu Y, Huang W, Tong B, Lu W . Total hysterectomy versus uterine evacuation for preventing post-molar gestational trophoblastic neoplasia in patients who are at least 40 years old: a systematic review and meta-analysis. BMC Cancer. 2019; 19(1):13. PMC: 6322260. DOI: 10.1186/s12885-018-5168-x. View

10.

Brown J, Naumann R, Seckl M, Schink J . 15years of progress in gestational trophoblastic disease: Scoring, standardization, and salvage. Gynecol Oncol. 2016; 144(1):200-207. DOI: 10.1016/j.ygyno.2016.08.330. View

11.

Alifrangis C, Agarwal R, Short D, Fisher R, Sebire N, Harvey R . EMA/CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis. J Clin Oncol. 2012; 31(2):280-6. DOI: 10.1200/JCO.2012.43.1817. View

12.

Seckl M, Sebire N, Fisher R, Golfier F, Massuger L, Sessa C . Gestational trophoblastic disease: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013; 24 Suppl 6:vi39-50. DOI: 10.1093/annonc/mdt345. View

13.

Kaczmarek J, Kates R, Rau F, Kohorn E, Curry S . Intrapartum uterine rupture in a primiparous patient previously treated for invasive mole. Obstet Gynecol. 1994; 83(5 Pt 2):842-4. View