» Articles » PMID: 35154776

Unmasking of Addison's Disease in COVID-19

Overview
Publisher Sage Publications
Specialty General Medicine
Date 2022 Feb 14
PMID 35154776
Authors
Affiliations
Soon will be listed here.
Abstract

This case report highlights the initial presentation of Addison's disease in a 19-year-old individual with coronavirus disease. Coronavirus disease is an infectious disease, which often presents with fever and respiratory and gastrointestinal symptoms. Here, we describe a challenging case of a patient with coronavirus disease, who initially presented with altered mental status, hyponatremia, and cerebral edema, with subsequent workup leading to the diagnosis of Addison's disease.

Citing Articles

COVID-19 and Adrenal Insufficiency: Unmasking the Link.

Marques C, Almeida P, Goncalves A, Nagirnyak V, Cabeleira J Cureus. 2023; 15(10):e47920.

PMID: 38034146 PMC: 10684291. DOI: 10.7759/cureus.47920.


The Impact of COVID-19 on the Cardiovascular Health of Emerging Adults Aged 18-25: Findings From a Scoping Review.

Rezler Z, Ko E, Jin E, Ishtiaq M, Papaioannou C, Kim H CJC Pediatr Congenit Heart Dis. 2023; 2(1):33-50.

PMID: 37970101 PMC: 9711905. DOI: 10.1016/j.cjcpc.2022.11.005.


Evaluation of the hypothalamo-pituitary-adrenal axis during the post-COVID-19 period in patients treated with steroids during the illness.

C M S, Ramesh J Arch Endocrinol Metab. 2023; 68:e220207.

PMID: 37948563 PMC: 10916833. DOI: 10.20945/2359-4292-2022-0207.


Sequence similarity between SARS-CoV-2 nucleocapsid and multiple sclerosis-associated proteins provides insight into viral neuropathogenesis following infection.

Lake C, Breen J Sci Rep. 2023; 13(1):389.

PMID: 36617594 PMC: 9825799. DOI: 10.1038/s41598-022-27348-8.


Newly diagnosed autoimmune Addison's disease in a patient with COVID-19 with autoimmune disseminated encephalomyelitis.

Beshay L, Wei K, Yang Q BMJ Case Rep. 2023; 15(12).

PMID: 36593594 PMC: 9723877. DOI: 10.1136/bcr-2022-250749.


References
1.
Kumar R, Guruparan T, Siddiqi S, Sheth R, Jacyna M, Naghibi M . A case of adrenal infarction in a patient with COVID 19 infection. BJR Case Rep. 2020; 6(3):20200075. PMC: 7465735. DOI: 10.1259/bjrcr.20200075. View

2.
Natarajan R, Ploszaj S, Horton R, Nadler J . Tumor necrosis factor and interleukin-1 are potent inhibitors of angiotensin-II-induced aldosterone synthesis. Endocrinology. 1989; 125(6):3084-9. DOI: 10.1210/endo-125-6-3084. View

3.
Isidori A, Arnaldi G, Boscaro M, Falorni A, Giordano C, Giordano R . COVID-19 infection and glucocorticoids: update from the Italian Society of Endocrinology Expert Opinion on steroid replacement in adrenal insufficiency. J Endocrinol Invest. 2020; 43(8):1141-1147. PMC: 7182741. DOI: 10.1007/s40618-020-01266-w. View

4.
Pascarella G, Strumia A, Piliego C, Bruno F, Del Buono R, Costa F . COVID-19 diagnosis and management: a comprehensive review. J Intern Med. 2020; 288(2):192-206. PMC: 7267177. DOI: 10.1111/joim.13091. View

5.
McLachlan C . The angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms. Clin Hypertens. 2020; 26:14. PMC: 7360378. DOI: 10.1186/s40885-020-00147-x. View