Behavioral and Neuroimaging Research on Developmental Coordination Disorder (DCD): A Combined Systematic Review and Meta-Analysis of Recent Findings

Overview

Journal Front Psychol

Date 2022 Feb 14

PMID 35153960

Authors

Emily Subara-Zukic

Michael H Cole

Thomas B McGuckian

Bert Steenbergen

Dido Green

Bouwien Cm Smits-Engelsman

Jessica M Lust

Reza Abdollahipour

Erik Domellof

Frederik J A Deconinck

Rainer Blank

Peter H Wilson

Affiliations

Soon will be listed here.

Abstract

Aim: The neurocognitive basis of Developmental Coordination Disorder (DCD; or motor clumsiness) remains an issue of continued debate. This combined systematic review and meta-analysis provides a synthesis of recent experimental studies on the motor control, cognitive, and neural underpinnings of DCD.

Methods: The review included all published work conducted since September 2016 and up to April 2021. One-hundred papers with a DCD-Control comparison were included, with 1,374 effect sizes entered into a multi-level meta-analysis.

Results: The most profound deficits were shown in: voluntary gaze control during movement; cognitive-motor integration; practice-/context-dependent motor learning; internal modeling; more variable movement kinematics/kinetics; larger safety margins when locomoting, and atypical neural structure and function across sensori-motor and prefrontal regions.

Interpretation: Taken together, these results on DCD suggest fundamental deficits in visual-motor mapping and cognitive-motor integration, and abnormal maturation of motor networks, but also areas of pragmatic compensation for motor control deficits. Implications for current theory, future research, and evidence-based practice are discussed.

Systematic Review Registration: PROSPERO, identifier: CRD42020185444.

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References

Diz M, Ferracioli M, Hiraga C, Oliveira M, Pellegrini A . Effects of practice on visual finger-force control in children at risk of developmental coordination disorder. Braz J Phys Ther. 2018; 22(6):467-473. PMC: 6235753. DOI: 10.1016/j.bjpt.2018.04.002. View

Rahimi-Golkhandan S, Steenbergen B, Piek J, Caeyenberghs K, Wilson P . Revealing hot executive function in children with motor coordination problems: What's the go?. Brain Cogn. 2016; 106:55-64. DOI: 10.1016/j.bandc.2016.04.010. View

Adi-Japha E, Brestel G . Motor skill learning with impaired transfer by children with developmental coordination disorder. Res Dev Disabil. 2020; 103:103671. DOI: 10.1016/j.ridd.2020.103671. View

Gillberg C, Kadesjo B . Why bother about clumsiness? The implications of having developmental coordination disorder (DCD). Neural Plast. 2003; 10(1-2):59-68. PMC: 2565425. DOI: 10.1155/NP.2003.59. View

Higgins J, Thompson S . Quantifying heterogeneity in a meta-analysis. Stat Med. 2002; 21(11):1539-58. DOI: 10.1002/sim.1186. View

Adams I, Lust J, Steenbergen B . Development of motor imagery ability in children with developmental coordination disorder - A goal-directed pointing task. Br J Psychol. 2017; 109(2):187-203. DOI: 10.1111/bjop.12274. View

Golenia L, Bongers R, van Hoorn J, Otten E, Mouton L, Schoemaker M . Variability in coordination patterns in children with developmental coordination disorder (DCD). Hum Mov Sci. 2018; 60:202-213. DOI: 10.1016/j.humov.2018.06.009. View

Brown-Lum M, Izadi-Najafabadi S, Oberlander T, Rauscher A, Zwicker J . Differences in White Matter Microstructure Among Children With Developmental Coordination Disorder. JAMA Netw Open. 2020; 3(3):e201184. PMC: 7081126. DOI: 10.1001/jamanetworkopen.2020.1184. View

Smith M, Ward E, Williams C, Banwell H . Differences in walking and running gait in children with and without developmental coordination disorder: A systematic review and meta-analysis. Gait Posture. 2020; 83:177-184. DOI: 10.1016/j.gaitpost.2020.10.013. View

10.

Bhoyroo R, Hands B, Wilmut K, Hyde C, Wigley A . Motor planning with and without motor imagery in children with Developmental Coordination Disorder. Acta Psychol (Amst). 2019; 199:102902. DOI: 10.1016/j.actpsy.2019.102902. View

11.

Smits-Engelsman B, Vincon S, Blank R, Quadrado V, Polatajko H, Wilson P . Evaluating the evidence for motor-based interventions in developmental coordination disorder: A systematic review and meta-analysis. Res Dev Disabil. 2018; 74:72-102. DOI: 10.1016/j.ridd.2018.01.002. View

12.

Poirier G, Ohayon A, Juranville A, Mourey F, Gaveau J . Deterioration, Compensation and Motor Control Processes in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease. Geriatrics (Basel). 2021; 6(1). PMC: 8006018. DOI: 10.3390/geriatrics6010033. View

13.

Gentle J, Barnett A, Wilmut K . Adaptations to walking on an uneven terrain for individuals with and without Developmental Coordination Disorder. Hum Mov Sci. 2016; 49:346-53. DOI: 10.1016/j.humov.2016.08.010. View

14.

Visser J . Developmental coordination disorder: a review of research on subtypes and comorbidities. Hum Mov Sci. 2003; 22(4-5):479-93. DOI: 10.1016/j.humov.2003.09.005. View

15.

Hyde C, Fuelscher I, Williams J, Lum J, He J, Barhoun P . Corticospinal excitability during motor imagery is reduced in young adults with developmental coordination disorder. Res Dev Disabil. 2017; 72:214-224. DOI: 10.1016/j.ridd.2017.11.009. View

16.

Koziol L, Budding D, Chidekel D . From movement to thought: executive function, embodied cognition, and the cerebellum. Cerebellum. 2011; 11(2):505-25. DOI: 10.1007/s12311-011-0321-y. View

17.

Adams I, Lust J, Wilson P, Steenbergen B . Development of motor imagery and anticipatory action planning in children with developmental coordination disorder - A longitudinal approach. Hum Mov Sci. 2017; 55:296-306. DOI: 10.1016/j.humov.2017.08.021. View

18.

Yam T, Fong S . Y-Balance Test Performance and Leg Muscle Activations of Children with Developmental Coordination Disorder. J Mot Behav. 2018; 51(4):385-393. DOI: 10.1080/00222895.2018.1485011. View

19.

Fong S, Chung J, Cheng Y, Yam T, Chiu H, Fong D . Attention during functional tasks is associated with motor performance in children with developmental coordination disorder: A cross-sectional study. Medicine (Baltimore). 2016; 95(37):e4935. PMC: 5402615. DOI: 10.1097/MD.0000000000004935. View

20.

Hyde C, Fuelscher I, Enticott P, Jones D, Farquharson S, Silk T . White matter organization in developmental coordination disorder: A pilot study exploring the added value of constrained spherical deconvolution. Neuroimage Clin. 2018; 21:101625. PMC: 6411781. DOI: 10.1016/j.nicl.2018.101625. View