Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?

Overview

Journal J Stroke

Date 2022 Feb 8

PMID 35135057

Authors

Hai-Jie Liang

Qing-Yi Zhang

Yi-Tong Hu

Guo-Qing Liu

Rong Qi

Affiliations

Soon will be listed here.

Abstract

Hypertriglyceridemia is caused by defects in triglyceride metabolism and generally manifests as abnormally high plasma triglyceride levels. Although the role of hypertriglyceridemia may not draw as much attention as that of plasma cholesterol in stroke, plasma triglycerides, especially nonfasting triglycerides, are thought to be correlated with the risk of ischemic stroke. Hypertriglyceridemia may increase the risk of ischemic stroke by promoting atherosclerosis and thrombosis and increasing blood viscosity. Moreover, hypertriglyceridemia may have some protective effects in patients who have already suffered a stroke via unclear mechanisms. Therefore, further studies are needed to elucidate the role of hypertriglyceridemia in the development and prognosis of ischemic stroke.

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