Literature Review of the Mechanisms of Acute Kidney Injury Secondary to Acute Liver Injury

Overview

Journal World J Nephrol

Publisher Baishideng Publishing Group

Specialty Nephrology

Date 2022 Feb 4

PMID 35117976

Authors

Esther Platt

Enriko Klootwijk

Alan Salama

Brian Davidson

Francis Robertson

Affiliations

Soon will be listed here.

Abstract

People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality. Molecular mediators released by the liver in response to IR injury are the likely cause of acute kidney injury (AKI) in this setting, but the mediators have not yet been identified. Identifying the mechanism of injury will allow the identification of therapeutic targets which may modulate both liver IR injury and AKI following liver IR injury.

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