Adjuvant Radiotherapy for Low-risk Early Breast Cancer in Elderly Women: Evidence from Randomized Trials

Overview

Journal Transl Cancer Res

Specialty Oncology

Date 2022 Feb 4

PMID 35117964

Authors

Javier Burgos-Burgos

Beatriz Pinar-Sedeno

Laura Garcia-Cabrera

Nieves Rodriguez-Ibarria

Auxiliadora Cabezon-Pons

Marta Lloret-Saenz-Bravo

Elena Vicente-Rubio

Victor Vega-Benitez

Maria Travieso-Aja

Pedro C Lara

Affiliations

Soon will be listed here.

Abstract

Breast cancer is the most common cancer pathology in women in the Western world. The median age at diagnosis is 60 years and in the coming decades it is estimated that the number of elderly women affected reaches an important percentage. This aging of the cancer population, associated with its inherent comorbidities and aggravated by the lack of consensus about the most appropriate treatment, make it difficult to administer an effective postoperative treatment in elderly women with a low-risk profile. An exhaustive geriatric evaluation is a sine qua non condition to opt for a specific type of treatment. To date, several options are available such as endocrine therapy (ET) alone, moderate/high hypofractionation and various accelerated partial breast irradiation (APBI) techniques. In this article, we provide information about each of them.

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