Analysis of Autozygosity Using Whole-Genome Sequence Data of Full-Sib Families in Pikeperch ()

Overview

Journal Front Genet

Date 2022 Feb 3

PMID 35111201

Authors

Lidia De Los Rios-Perez

Tom Druet

Tom Goldammer

Dorte Wittenburg

Affiliations

Soon will be listed here.

Abstract

Pikeperch () has emerged as a high value species to the aquaculture industry. However, its farming techniques are at an early stage and its production is often performed without a selective breeding program, potentially leading to high levels of inbreeding. In this study, we identified and characterized autozygosity based on genome-wide runs of homozygosity (ROH) on a sample of parental and offspring individuals, determined effective population size ( ), and assessed relatedness among parental individuals. A mean of 2,235 ± 526 and 1,841 ± 363 ROH segments per individual, resulting in a mean inbreeding coefficient of 0.33 ± 0.06 and 0.25 ± 0.06 were estimated for the progeny and parents, respectively. was about 12 until four generations ago and at most 106 for 63 generations in the past, with varying genetic relatedness amongst the parents. This study shows the importance of genomic information when family relationships are unknown and the need of selective breeding programs for reproductive management decisions in the aquaculture industry.

Citing Articles

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Novo I, Ordas P, Moraga N, Santiago E, Quesada H, Caballero A Genet Sel Evol. 2023; 55(1):86.

PMID: 38049712 PMC: 10694967. DOI: 10.1186/s12711-023-00859-2.

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