» Articles » PMID: 35105327

Heterogeneity in Gender Dysphoria in a Brazilian Sample Awaiting Gender-affirming Surgery: a Data-driven Analysis

Overview
Journal BMC Psychiatry
Publisher Biomed Central
Specialty Psychiatry
Date 2022 Feb 2
PMID 35105327
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Population heterogeneity and the lack of clinical and sociodemographic information in transgender individuals with gender dysphoria (GD) remains a challenge for specialized services in mental health and surgical procedures. It aimed to identify and describe profiles in a sample waiting for gender-affirming surgery.

Methods: A sample of 100 outpatients with GD was assessed through a structured interview, Emotion Regulation Difficulty Scale (DERS), Ruminative Response Scale (RRS), Depression, Anxiety and Stress Scale (DASS-21) and Life Satisfaction scale (SWLS). Cluster analysis was used to identify different profile categories.

Results: Two subgroups with different profiles were identified: with less clinical severity (LCS) and with high clinical severity (HCS) on emotional dysregulation, acute symptoms of depression, anxiety, stress and association with mental rumination. The HCS cluster had greater vulnerability in terms of psychiatric history, use of psychotropic drugs, HIV positive, child abuse and suicidal behavior.

Conclusion: Different profiles were found regarding the vulnerability to mental health in a sample of transgender people with GD who seek a public hospital service for the same clinical-surgical objective. Longitudinal studies are essential to monitor the impact of these contrasts and to target personalized therapeutic approaches in the prevention of psychiatric disorders.

Citing Articles

Medical care for transgender individuals at a hospital in southern Brazil: why do they drop out from our service?.

Guadagnin F, Schwarz K, Cardoso da Silva D, Salati L, Kayser V, Lobato M Front Public Health. 2024; 12:1254875.

PMID: 39081350 PMC: 11288249. DOI: 10.3389/fpubh.2024.1254875.


A scoping review of the clinical application of machine learning in data-driven population segmentation analysis.

Liu P, Wang Z, Liu N, Peres M J Am Med Inform Assoc. 2023; 30(9):1573-1582.

PMID: 37369006 PMC: 10436153. DOI: 10.1093/jamia/ocad111.

References
1.
Mueller A, Quadros C, Schwarz K, Costa A, Fontanari A, Soll B . Rumination as a Marker of Psychological Improvement in Transsexual Women Postoperative. Transgend Health. 2017; 1(1):274-278. PMC: 5367481. DOI: 10.1089/trgh.2016.0029. View

2.
Dhejne C, Van Vlerken R, Heylens G, Arcelus J . Mental health and gender dysphoria: A review of the literature. Int Rev Psychiatry. 2016; 28(1):44-57. DOI: 10.3109/09540261.2015.1115753. View

3.
Fontanari A, Vianna L, Schneider M, Soll B, Schwarz K, Cardoso da Silva D . A Retrospective Review of Medical Records of Laboratory-Tested Sexually Transmitted Infections of Transsexual Men from Southern Brazil. Arch Sex Behav. 2019; 48(5):1573-1579. DOI: 10.1007/s10508-019-1395-8. View

4.
Christodoulou E, Ma J, Collins G, Steyerberg E, Verbakel J, Van Calster B . A systematic review shows no performance benefit of machine learning over logistic regression for clinical prediction models. J Clin Epidemiol. 2019; 110:12-22. DOI: 10.1016/j.jclinepi.2019.02.004. View

5.
Cardoso da Silva D, Schwarz K, Fontanari A, Costa A, Massuda R, Henriques A . WHOQOL-100 Before and After Sex Reassignment Surgery in Brazilian Male-to-Female Transsexual Individuals. J Sex Med. 2016; 13(6):988-93. DOI: 10.1016/j.jsxm.2016.03.370. View