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Nerve Block on Pain After Mammaplasty: A Meta-Analysis of Randomized Controlled Studies

Overview
Specialty General Surgery
Date 2022 Jan 31
PMID 35096690
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Abstract

Background: Nerve block showed some potential in alleviating pain after mammaplasty. This systematic review and meta-analysis was conducted to investigate the efficacy of nerve block for pain control after mammaplasty.

Methods: The databases including PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases were systematically searched for collecting the randomized controlled trials (RCTs) regarding the impact of nerve block on pain intensity after mammaplasty.

Results: This meta-analysis included 4 RCTs. Compared with control group after mammaplasty, nerve block resulted in remarkably reduced pain scores at 1 hour (mean difference [MD] = -1.84; 95% CI = -2.49 to -1.20; < .00001), 3 hours (MD = -1.04; 95% CI = -1.47 to -0.62; < .00001), 6 hours (MD = -0.96; 95% CI = -1.48 to -0.43; = .0004), and analgesic consumption (standard mean difference = -1.27; 95% CI = -1.73 to -0.82; < .00001), but showed no significant impact on pain scores within 24 hours (MD = -0.31; 95% CI = -1.05 to 0.43; = .41).

Conclusions: Nerve block was associated with substantially reduced pain intensity after mammaplasty.

References
1.
Gurkan Y, Aksu C, Kus A, Yorukoglu U, Kilic C . Ultrasound guided erector spinae plane block reduces postoperative opioid consumption following breast surgery: A randomized controlled study. J Clin Anesth. 2018; 50:65-68. DOI: 10.1016/j.jclinane.2018.06.033. View

2.
Schnabel A, Reichl S, Kranke P, Pogatzki-Zahn E, Zahn P . Efficacy and safety of paravertebral blocks in breast surgery: a meta-analysis of randomized controlled trials. Br J Anaesth. 2010; 105(6):842-52. DOI: 10.1093/bja/aeq265. View

3.
Jadad A, Moore R, Carroll D, Jenkinson C, Reynolds D, Gavaghan D . Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials. 1996; 17(1):1-12. DOI: 10.1016/0197-2456(95)00134-4. View

4.
Steyaert A, Forget P, Dubois V, Lavandhomme P, De Kock M . Does the perioperative analgesic/anesthetic regimen influence the prevalence of long-term chronic pain after mastectomy?. J Clin Anesth. 2016; 33:20-5. DOI: 10.1016/j.jclinane.2015.07.010. View

5.
Onishi E, Murakami M, Nishino R, Ohba R, Yamauchi M . Analgesic Effect of Double-Level Retrolaminar Paravertebral Block for Breast Cancer Surgery in the Early Postoperative Period: A Placebo-Controlled, Randomized Clinical Trial. Tohoku J Exp Med. 2018; 245(3):179-185. DOI: 10.1620/tjem.245.179. View