Thermal Dysregulation in Patients with Multiple Sclerosis During SARS-CoV-2 Infection. The Potential Therapeutic Role of Exercise

Overview

Journal Mult Scler Relat Disord

Specialty Neurology

Date 2022 Jan 29

PMID 35092946

Authors

Omid Razi

Bakhtyar Tartibian

Ana Maria Teixeira

Nastaran Zamani

Karuppasamy Govindasamy

Katsuhiko Suzuki

Ismail Laher

Hassane Zouhal

Affiliations

Soon will be listed here.

Abstract

Thermoregulation is a homeostatic mechanism that is disrupted in some neurological diseases. Patients with multiple sclerosis (MS) are susceptible to increases in body temperature, especially with more severe neurological signs. This condition can become intolerable when these patients suffer febrile infections such as coronavirus disease-2019 (COVID-19). We review the mechanisms of hyperthermia in patients with MS, and they may encounter when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Finally, the thermoregulatory role and relevant adaptation to regular physical exercise are summarized.

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