Metabolomics Based Biomarker Identification of Anti-diabetes and Anti-obesity Properties of Malaysian Herbs

Overview

Journal Metabolomics

Publisher Springer

Specialty Endocrinology

Date 2022 Jan 29

PMID 35092490

Authors

Khaled Benchoula

Muhammad Sufyan Vohra

Ishwar S Parhar

Wong Eng Hwa

Affiliations

Soon will be listed here.

Abstract

Background: Today, obesity affects over one-third of the global population and is hugely considered the Industrial Revolution's side effect. This multi-factorial disease is continuously spreading across developing countries, including the Middle East and Southeast Asia region, where Malaysia and Darussalam Brunei are the most affected. The sedentary lifestyle and availability of surplus foods have dramatically increased the number of individuals with type 2 diabetes in these countries. Thus, an adequate medical strategy must be developed urgently to address and remedy these diseases. Natural sources have been attracting attention, especially in Malaysia, where most land areas are under plant cover. Metabolomics, as a prophylactic technique, has been used extensively in Malaysia to investigate the potential use and benefits of herbs to combat obesity and diabetes.

Aim Of Review: This review aims to explain the application of the metabolomics approach in the study of anti-diabetes and anti-obesity activity of Malaysian herbs to identify the stand-up point for future advancement in using these herbs as a primary source for drug exploration.

Key Scientific Concepts Of Review: This review provides an overview of using metabolomics technique in studying the anti-diabetes and anti-obesity activity of Malaysian herbs. Specific emphasis is given to the changed metabolites in both in vivo and in vitro treatment of Malaysia herbs that might be future drugs for treating diabetes and obesity.

Citing Articles

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