» Articles » PMID: 35078282

[Pattern of Recurrence and Metastasis After Radical Resection of 
Non-small Cell Lung Cancer]

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Date 2022 Jan 25
PMID 35078282
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Abstract

The rate of recurrence and metastasis of non-small cell lung cancer after radical resection is still very high. The risk factors for recurrence and metastasis have been extensively studied, but the dynamic pattern of postoperative recurrence hazard over time is relatively lacking. The dynamic recurrence hazard rate curve is applied to describe the rate of recurrence at any point time among the "at-risk" patients. In this article, by reviewing the previous literature, the characteristics of the dynamic recurrence and metastasis pattern after radical resection of non-small cell lung cancer and the clinical factors affecting the recurrence and metastasis pattern are summarized, in order to screen out specific populations with high recurrence risk and give them personalized follow-up strategy and diagnosis and treatment.
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References
1.
Brandt W, Bouabdallah I, Tan K, Park B, Adusumilli P, Molena D . Factors associated with distant recurrence following R0 lobectomy for pN0 lung adenocarcinoma. J Thorac Cardiovasc Surg. 2017; 155(3):1212-1224.e3. PMC: 5816702. DOI: 10.1016/j.jtcvs.2017.09.151. View

2.
Wong M, McMurry T, Stukenborg G, Francescatti A, Amato-Martz C, Schumacher J . Impact of age and comorbidity on treatment of non-small cell lung cancer recurrence following complete resection: A nationally representative cohort study. Lung Cancer. 2016; 102:108-117. PMC: 5172386. DOI: 10.1016/j.lungcan.2016.11.002. View

3.
Hashimoto M, Tanaka F, Yoneda K, Takuwa T, Matsumoto S, Okumura Y . Significant increase in circulating tumour cells in pulmonary venous blood during surgical manipulation in patients with primary lung cancer. Interact Cardiovasc Thorac Surg. 2014; 18(6):775-83. DOI: 10.1093/icvts/ivu048. View

4.
Kim J, Bae J . Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment. Mediators Inflamm. 2016; 2016:6058147. PMC: 4757693. DOI: 10.1155/2016/6058147. View

5.
Pantel K, Brakenhoff R, Brandt B . Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Cancer. 2008; 8(5):329-40. DOI: 10.1038/nrc2375. View