» Articles » PMID: 35075415

Clinical Applications of Aspirin As a Multi-potent Drug Beyond Cardiovascular Implications: A Proof of Concept for Anesthesiologists- A Narrative Review

Overview
Journal Anesth Pain Med
Publisher Brieflands
Date 2022 Jan 25
PMID 35075415
Authors
Affiliations
Soon will be listed here.
Abstract

To the best of our knowledge, aspirin (ASA) is known as a commonly used medication worldwide. Although the cardiovascular aspects of ASA are well-established, recently, it has been identified that ASA can yield multiple extra-cardiovascular therapeutic potencies in facing neurodegenerative disorders, various cancers, inflammatory responses, and the COVID-19 pandemic. In this review, we aimed to highlight the proven role of ASA administration in the variety of non-cardiovascular diseases, particularly in the field of anesthesiology.

Citing Articles

Aspirin Inhibits the In Vitro Adipogenic Differentiation of Human Adipose Tissue-Derived Stem Cells in a Dose-Dependent Manner.

Funke S, Wiggenhauser P, Grundmeier A, Fuchs B, Koban K, Demmer W Int J Mol Sci. 2025; 26(2).

PMID: 39859567 PMC: 11766433. DOI: 10.3390/ijms26020853.


Ethanolic Extracts of Linn. (Vitaceae) Attenuate Vincristine-Induced Peripheral Neuropathy in Rats: An Evidence of the Antioxidant, Calcium Inhibitory, and Neuromodulatory Properties.

Olga F, Marius M, William Y, Gonzal T, Flore D, Chretien N Adv Pharmacol Pharm Sci. 2024; 2024:8822369.

PMID: 39703364 PMC: 11658851. DOI: 10.1155/adpp/8822369.


Aspirin Stimulates the Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells In Vitro.

Funke S, Wiggenhauser P, Grundmeier A, Taha S, Fuchs B, Birt A Int J Mol Sci. 2024; 25(14).

PMID: 39062933 PMC: 11277042. DOI: 10.3390/ijms25147690.


Bibliometric Analysis of Anesthetic Drugs' Effects on Immune Function- Current Knowledge, Hotspots and Future Perspectives.

Wang Y, Sun Y, Hu Y, Xiao Z Drug Des Devel Ther. 2023; 17:3219-3230.

PMID: 37908313 PMC: 10615110. DOI: 10.2147/DDDT.S433629.


Non-opioid Intravenous Drugs for Pain Management in Patients Presenting with Acute Migraine Pain in the Emergency Department: A Comprehensive Literature Review.

Zarei M, Hajipoor Kashgsaray N, Asheghi M, Shahabifard H, Soleimanpour H Anesth Pain Med. 2023; 12(5):e132904.

PMID: 36937180 PMC: 10016134. DOI: 10.5812/aapm-132904.


References
1.
OBrien M, Hunt P, Kitch D, Klingman K, Stein J, Funderburg N . A Randomized Placebo Controlled Trial of Aspirin Effects on Immune Activation in Chronically Human Immunodeficiency Virus-Infected Adults on Virologically Suppressive Antiretroviral Therapy. Open Forum Infect Dis. 2017; 4(1):ofw278. PMC: 5414028. DOI: 10.1093/ofid/ofw278. View

2.
El-Achi V, Park F, OBrien C, Tooher J, Hyett J . Does low dose aspirin prescribed for risk of early onset preeclampsia reduce the prevalence of preterm prelabor rupture of membranes?. J Matern Fetal Neonatal Med. 2019; 34(4):618-623. DOI: 10.1080/14767058.2019.1611768. View

3.
Berger J, Lala A, Krantz M, Baker G, Hiatt W . Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: a meta-analysis of randomized trials. Am Heart J. 2011; 162(1):115-24.e2. DOI: 10.1016/j.ahj.2011.04.006. View

4.
Javaherforoosh Zadeh F, Janatmakan F, Shafaee Tonekaboni M, Soltanzadeh M . The Effect of Fibrinogen on Blood Loss After Lumbar Surgery: A Double-Blind Randomized Clinical Trial. Anesth Pain Med. 2019; 9(3):e91199. PMC: 6712358. DOI: 10.5812/aapm.91199. View

5.
Haykal T, Barbarawi M, Zayed Y, Yelangi A, Dhillon H, Goranta S . Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials. J Cancer Res Clin Oncol. 2019; 145(7):1795-1809. DOI: 10.1007/s00432-019-02932-0. View