Disease Criteria of Systemic Lupus Erythematosus (SLE); the Potential Role of Non-criteria Autoantibodies

Overview

Journal J Transl Autoimmun

Date 2022 Jan 24

PMID 35072035

Authors

Juan Irure-Ventura

Marcos Lopez-Hoyos

Affiliations

Soon will be listed here.

Abstract

Patients with SLE show a broad spectrum of more than 200 autoantibodies. They can be pathogenic, predictive, prognostic or even an epiphenomenon. Here, we discuss different autoantibodies that have not been included in EULAR/ACR 2019 classification criteria. Most of them have been addressed to monitor and detect disease activity and not specifically as classification criteria. Indeed, markers to assess disease activity fluctuate as compared with classification criteria and their validation is different. The development of new methods will probably bring new clinical associations and be evaluated as potential classification criteria.

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