Neural Substrates of the Drift-Diffusion Model in Brain Disorders

Overview

Journal Front Comput Neurosci

Specialty Biology

Date 2022 Jan 24

PMID 35069160

Authors

Ankur Gupta

Rohini Bansal

Hany Alashwal

Anil Safak Kacar

Fuat Balci

Ahmed A Moustafa

Affiliations

Soon will be listed here.

Abstract

Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex and basal ganglia. Furthermore, we discuss the changes in DDM parameters due to structural and functional impairments in several clinical disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Obsessive-Compulsive Disorder (OCD), and schizophrenia. This review thus uses DDM to provide a theoretical understanding of different brain disorders.

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