Antitumor Effects of Natural Compounds Derived from on Neuroblastoma: An Overview

Overview

Journal Antioxidants (Basel)

Date 2022 Jan 21

PMID 35052552

Authors

Carlos Cesar Patino-Morales

Ricardo Jaime-Cruz

Concepcion Sanchez-Gomez

Juan Carlos Corona

Estefani Yaquelin Hernandez-Cruz

Ivia Kalinova-Jelezova

Jose Pedraza-Chaverri

Perla D Maldonado

Carlos Alfredo Silva-Islas

Marcela Salazar-Garcia

Affiliations

Soon will be listed here.

Abstract

Garlic () has been used in alternative medicine to treat several diseases, such as cardiovascular and neurodegenerative diseases, cancer, and hepatic diseases. Several publications have highlighted other features of garlic, including its antibacterial, antioxidative, antihypertensive, and antithrombotic properties. The properties of garlic result from the combination of natural compounds that act synergistically and cause different effects. Some garlic-derived compounds have been studied for the treatment of several types of cancer; however, reports on the effects of garlic on neuroblastoma are scarce. Neuroblastoma is a prevalent childhood tumor for which the search for therapeutic alternatives to improve treatment without affecting the patients' quality of life continues. Garlic-derived compounds hold potential for the treatment of this type of cancer. A review of articles published to date on some garlic compounds and their effect on neuroblastoma was undertaken to comprehend the possible therapeutic role of these compounds. This review aimed to analyze the impact of some garlic compounds on cells derived from neuroblastoma.

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