» Articles » PMID: 35049946

Whole Genome Sequencing and Annotation of (Basidiomycota, Edible-Medicinal Fungi)

Overview
Journal J Fungi (Basel)
Date 2022 Jan 20
PMID 35049946
Authors
Affiliations
Soon will be listed here.
Abstract

is a rare edible fungus with both nutritional and medicinal values and especially rich in bioactive polysaccharides. However, due to the lack of genomic information, researches on the mining of active compounds, artificial breeding and cultivation, genetics, and molecular biology are limited. To facilitate the medicinal and food applications of , we sequenced and analyzed the whole genome of for the first time. The 21-Mb genome contained 15 contigs, and a total of 5860 protein-coding genes were predicted. The genome sequence shows that 296 genes are related to polysaccharide synthesis, including 15 genes related to nucleoside-activated sugar synthesis and 11 genes related to glucan synthesis. The genome also contains genes and gene clusters for the synthesis of other active substances, including terpenoids, unsaturated fatty acids, and bioactive proteins. In addition, it was also found that was more closely related to than to In short, this study provides a reference for molecular cognition of and related researches.

Citing Articles

A Chromosome-Scale Genome of and Transcriptome-Based Screening for Light-Induced Genes That Promote Triterpene Biosynthesis.

Yang Y, Hu X J Fungi (Basel). 2025; 11(1).

PMID: 39852500 PMC: 11766705. DOI: 10.3390/jof11010081.


Genome Sequencing Providing Molecular Evidence of Tetrapolar Mating System and Heterothallic Life Cycle for Edible and Medicinal Mushroom Fr.

Li S, Liu Y, Liu L, Li B, Guo S J Fungi (Basel). 2025; 11(1).

PMID: 39852434 PMC: 11766841. DOI: 10.3390/jof11010015.


Chromosome-Level Assembly Reveals a Fifteen-Chromosome Aneuploid Genome and Environmental Adaptation Strategy of Chinese Traditional Medical Fungus .

Li S, Li B, Guo S Int J Mol Sci. 2024; 25(16).

PMID: 39201472 PMC: 11354754. DOI: 10.3390/ijms25168786.


Chromosome-Level Assembly and Comparative Genomic Analysis of Provides Insights into the Mechanism of Mycorrhizal Symbiosis.

Zhang J, An M, Chen Y, Wang S, Liang J J Fungi (Basel). 2024; 10(3).

PMID: 38535219 PMC: 10971629. DOI: 10.3390/jof10030211.


Chromosome-level assembly of Dictyophora rubrovolvata genome using third-generation DNA sequencing and Hi-C analysis.

Ma L, Yang C, Xiao D, Liu X, Jiang X, Lin H G3 (Bethesda). 2023; 13(8).

PMID: 37178144 PMC: 10411574. DOI: 10.1093/g3journal/jkad102.


References
1.
Vilella A, Severin J, Ureta-Vidal A, Heng L, Durbin R, Birney E . EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates. Genome Res. 2008; 19(2):327-35. PMC: 2652215. DOI: 10.1101/gr.073585.107. View

2.
Yuan Q, Zhang X, Ma M, Long T, Xiao C, Zhang J . Immunoenhancing glucuronoxylomannan from Tremella aurantialba Bandoni et Zang and its low-molecular-weight fractions by radical depolymerization: Properties, structures and effects on macrophages. Carbohydr Polym. 2020; 238:116184. DOI: 10.1016/j.carbpol.2020.116184. View

3.
Bhattacharyya S, Sinha K, Sil P . Cytochrome P450s: mechanisms and biological implications in drug metabolism and its interaction with oxidative stress. Curr Drug Metab. 2014; 15(7):719-42. DOI: 10.2174/1389200215666141125121659. View

4.
Yang S, Yang X, Zhang H . Extracellular polysaccharide biosynthesis in . Crit Rev Microbiol. 2020; 46(4):359-380. DOI: 10.1080/1040841X.2020.1794788. View

5.
Yu Z, Wang E, Geng Y, Wang K, Chen D, Huang X . Complete genome analysis of strain SCCF01, a highly virulent isolate from the freshwater catfish. Virulence. 2019; 11(1):23-31. PMC: 6961728. DOI: 10.1080/21505594.2019.1702797. View