[Conservative Treatment Options for Arthritis of the Ankle : What is Possible, What is Effective?]

Overview

Journal Unfallchirurg

Date 2022 Jan 18

PMID 35041020

Authors

Jorg Jerosch

Affiliations

Soon will be listed here.

Abstract

In this article the causes of arthritis in the region of the ankle are introduced and the conservative treatment options are described and discussed more extensively. The risks of treatment with nonopioid analgesics (NOPA) are presented in detail. The topical use of nonsteroidal anti-inflammatory drugs (NSAID) should always be considered in the clinical routine. If contraindications for oral NSAIDs are present, intra-articular treatment is a meaningful option. The best evidence is currently available for viscosupplementation but the study situation for the use of platelet-rich plasma (PRP) is still not sufficiently comprehensive and there are only a few case reports on the use of mesenchymal stem cells..

Citing Articles

The efficacy of platelet-rich plasma in ankle disease: a systematic review and meta-analysis.

Ding Q, Wang X, Liu Y, Li Y, Zhang D, Wang H J Orthop Surg Res. 2024; 19(1):895.

PMID: 39741342 PMC: 11689593. DOI: 10.1186/s13018-024-05420-5.

References

Murphy E, Curtin M, McGoldrick N, Thong G, Kearns S . Prospective Evaluation of Intra-Articular Sodium Hyaluronate Injection in the Ankle. J Foot Ankle Surg. 2017; 56(2):327-331. DOI: 10.1053/j.jfas.2016.09.017. View

Schmid T, Krause F . Conservative treatment of asymmetric ankle osteoarthritis. Foot Ankle Clin. 2013; 18(3):437-48. DOI: 10.1016/j.fcl.2013.06.003. View

Sun S, Hsu C, Sun H, Chou Y, Li H, Wang J . The effect of three weekly intra-articular injections of hyaluronate on pain, function, and balance in patients with unilateral ankle arthritis. J Bone Joint Surg Am. 2011; 93(18):1720-6. DOI: 10.2106/JBJS.J.00315. View

Fukawa T, Yamaguchi S, Akatsu Y, Yamamoto Y, Akagi R, Sasho T . Safety and Efficacy of Intra-articular Injection of Platelet-Rich Plasma in Patients With Ankle Osteoarthritis. Foot Ankle Int. 2017; 38(6):596-604. DOI: 10.1177/1071100717700377. View

Kuettner K, Cole A . Cartilage degeneration in different human joints. Osteoarthritis Cartilage. 2005; 13(2):93-103. DOI: 10.1016/j.joca.2004.11.006. View

Bossert M, Boublil D, Parisaux J, Bozgan A, Richelme E, Conrozier T . Imaging Guidance Improves the Results of Viscosupplementation with HANOX-M-XL in Patients with Ankle Osteoarthritis: Results of a Clinical Survey in 50 Patients Treated in Daily Practice. Clin Med Insights Arthritis Musculoskelet Disord. 2016; 9:195-199. PMC: 5120624. DOI: 10.4137/CMAMD.S40401. View

Carpenter B, Motley T . The role of viscosupplementation in the ankle using hylan G-F 20. J Foot Ankle Surg. 2008; 47(5):377-84. DOI: 10.1053/j.jfas.2008.06.013. View

Carulli C, Civinini R, Martini C, Linari S, Morfini M, Tani M . Viscosupplementation in haemophilic arthropathy: a long-term follow-up study. Haemophilia. 2011; 18(3):e210-4. DOI: 10.1111/j.1365-2516.2011.02654.x. View

Chang K, Hsiao M, Chen W, Wang T, Chien K . Effectiveness of intra-articular hyaluronic acid for ankle osteoarthritis treatment: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2012; 94(5):951-60. DOI: 10.1016/j.apmr.2012.10.030. View

10.

Furtado R, Machado F, da Luz K, Dos Santos M, Konai M, Lopes R . Intra-articular injection with triamcinolone hexacetonide in patients with rheumatoid arthritis: prospective assessment of goniometry and joint inflammation parameters. Rev Bras Reumatol Engl Ed. 2017; 57(2):115-121. DOI: 10.1016/j.rbre.2016.08.001. View

11.

Zheng H, Chen C . Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies. BMJ Open. 2015; 5(12):e007568. PMC: 4679914. DOI: 10.1136/bmjopen-2014-007568. View

12.

Grotle M, Hagen K, Natvig B, Dahl F, Kvien T . Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up. BMC Musculoskelet Disord. 2008; 9:132. PMC: 2573886. DOI: 10.1186/1471-2474-9-132. View

13.

Smith M, Nepple J, Wright R, Matava M, Brophy R . Knee Osteoarthritis Is Associated With Previous Meniscus and Anterior Cruciate Ligament Surgery Among Elite College American Football Athletes. Sports Health. 2016; 9(3):247-251. PMC: 5435150. DOI: 10.1177/1941738116683146. View

14.

Li H, George D, Jaarsma R, Mao X . Metabolic syndrome and components exacerbate osteoarthritis symptoms of pain, depression and reduced knee function. Ann Transl Med. 2016; 4(7):133. PMC: 4842398. DOI: 10.21037/atm.2016.03.48. View

15.

Aurich M, Albrecht D, Angele P, Becher C, Fickert S, Fritz J . [Treatment of Osteochondral Lesions in the Ankle: A Guideline from the Group "Clinical Tissue Regeneration" of the German Society of Orthopaedics and Traumatology (DGOU)]. Z Orthop Unfall. 2016; 155(1):92-99. DOI: 10.1055/s-0042-116330. View

16.

Zhang W, Doherty M, Arden N, Bannwarth B, Bijlsma J, Gunther K . EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2004; 64(5):669-81. PMC: 1755499. DOI: 10.1136/ard.2004.028886. View

17.

Felson D, Anderson J, Naimark A, Walker A, Meenan R . Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med. 1988; 109(1):18-24. DOI: 10.7326/0003-4819-109-1-18. View

18.

Gudbergsen H, Boesen M, Lohmander L, Christensen R, Henriksen M, Bartels E . Weight loss is effective for symptomatic relief in obese subjects with knee osteoarthritis independently of joint damage severity assessed by high-field MRI and radiography. Osteoarthritis Cartilage. 2012; 20(6):495-502. DOI: 10.1016/j.joca.2012.02.639. View

19.

Christensen P, Henriksen M, Bartels E, Leeds A, Larsen T, Gudbergsen H . Long-term weight-loss maintenance in obese patients with knee osteoarthritis: a randomized trial. Am J Clin Nutr. 2017; 106(3):755-763. DOI: 10.3945/ajcn.117.158543. View

20.

Deere K, Clinch J, Holliday K, McBeth J, Crawley E, Sayers A . Obesity is a risk factor for musculoskeletal pain in adolescents: findings from a population-based cohort. Pain. 2012; 153(9):1932-1938. DOI: 10.1016/j.pain.2012.06.006. View