The Physics of Cell Motility

Overview

Journal J Cell Sci Suppl

Specialty Cell Biology

Date 1987 Jan 1

PMID 3503893

Citations 47

Authors

G F Oster

A S Perelson

Affiliations

Soon will be listed here.

Abstract

Cell locomotion begins with a protrusion from the leading periphery of the cell. What drives this extension? Here we present a model for the extension of cell protuberances that unifies certain aspects of this phenomenon, and is based on the hypothesis that osmotic pressure drives cell extensions. This pressure arises from membrane-associated reactions, which liberate osmotically active particles, and from the swelling of the actin network that underlies the membrane.

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