The Special Role of CXCL13 in Lyme Neuroborreliosis: a Case Report
Overview
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The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, encephalomyelitis, encephalopathy and peripheral neuropathy. We report on a patient presenting with basal leptomeningoencephalitis associated with vasculopathy where the chemokine CXCL13 in cerebrospinal fluid played an important diagnostic role.
Are white matter hyperintensities associated with neuroborreliosis? The answer is twofold.
Lindland E, Rovang M, Solheim A, Andreassen S, Skarstein I, Dareez N Neuroradiology. 2024; 67(1):37-48.
PMID: 39422730 PMC: 11802615. DOI: 10.1007/s00234-024-03482-0.
CXCL13 in Cerebrospinal Fluid: Clinical Value in a Large Cross-Sectional Study.
Erhart D, Klose V, Schaper T, Tumani H, Senel M Int J Mol Sci. 2024; 25(1).
PMID: 38203597 PMC: 10779058. DOI: 10.3390/ijms25010425.