Graphene for Antimicrobial and Coating Application

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2022 Jan 11

PMID 35008923

Authors

Viritpon Srimaneepong

Hans Erling Skallevold

Zohaib Khurshid

Muhammad Sohail Zafar

Dinesh Rokaya

Janak Sapkota

Affiliations

Soon will be listed here.

Abstract

Graphene is a versatile compound with several outstanding properties, providing a combination of impressive surface area, high strength, thermal and electrical properties, with a wide array of functionalization possibilities. This review aims to present an introduction of graphene and presents a comprehensive up-to-date review of graphene as an antimicrobial and coating application in medicine and dentistry. Available articles on graphene for biomedical applications were reviewed from January 1957 to August 2020) using MEDLINE/PubMed, Web of Science, and ScienceDirect. The selected articles were included in this study. Extensive research on graphene in several fields exists. However, the available literature on graphene-based coatings in dentistry and medical implant technology is limited. Graphene exhibits high biocompatibility, corrosion prevention, antimicrobial properties to prevent the colonization of bacteria. Graphene coatings enhance adhesion of cells, osteogenic differentiation, and promote antibacterial activity to parts of titanium unaffected by the thermal treatment. Furthermore, the graphene layer can improve the surface properties of implants which can be used for biomedical applications. Hence, graphene and its derivatives may hold the key for the next revolution in dental and medical technology.

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References

Tepe G, Schmehl J, Wendel H, Schaffner S, Heller S, Gianotti M . Reduced thrombogenicity of nitinol stents--in vitro evaluation of different surface modifications and coatings. Biomaterials. 2005; 27(4):643-50. DOI: 10.1016/j.biomaterials.2005.06.004. View

Suo L, Jiang N, Wang Y, Wang P, Chen J, Pei X . The enhancement of osseointegration using a graphene oxide/chitosan/hydroxyapatite composite coating on titanium fabricated by electrophoretic deposition. J Biomed Mater Res B Appl Biomater. 2018; 107(3):635-645. DOI: 10.1002/jbm.b.34156. View

Wei D, Liu Y, Wang Y, Zhang H, Huang L, Yu G . Synthesis of N-doped graphene by chemical vapor deposition and its electrical properties. Nano Lett. 2009; 9(5):1752-8. DOI: 10.1021/nl803279t. View

Prasadh S, Suresh S, Wong R . Osteogenic Potential of Graphene in Bone Tissue Engineering Scaffolds. Materials (Basel). 2018; 11(8). PMC: 6120034. DOI: 10.3390/ma11081430. View

Xu Y, Cao H, Xue Y, Li B, Cai W . Liquid-Phase Exfoliation of Graphene: An Overview on Exfoliation Media, Techniques, and Challenges. Nanomaterials (Basel). 2018; 8(11). PMC: 6265730. DOI: 10.3390/nano8110942. View

Karagiannidis P, Hodge S, Lombardi L, Tomarchio F, Decorde N, Milana S . Microfluidization of Graphite and Formulation of Graphene-Based Conductive Inks. ACS Nano. 2017; 11(3):2742-2755. PMC: 5371927. DOI: 10.1021/acsnano.6b07735. View

Rokaya D, Srimaneepong V, Sapkota J, Qin J, Siraleartmukul K, Siriwongrungson V . Polymeric materials and films in dentistry: An overview. J Adv Res. 2018; 14:25-34. PMC: 6198729. DOI: 10.1016/j.jare.2018.05.001. View

Novoselov K, Geim A, Morozov S, Jiang D, Zhang Y, Dubonos S . Electric field effect in atomically thin carbon films. Science. 2004; 306(5696):666-9. DOI: 10.1126/science.1102896. View

Novoselov K, Falko V, Colombo L, Gellert P, Schwab M, Kim K . A roadmap for graphene. Nature. 2012; 490(7419):192-200. DOI: 10.1038/nature11458. View

10.

Shearer C, Slattery A, Stapleton A, Shapter J, Gibson C . Accurate thickness measurement of graphene. Nanotechnology. 2016; 27(12):125704. DOI: 10.1088/0957-4484/27/12/125704. View

11.

Dubey N, Bentini R, Islam I, Cao T, Castro Neto A, Rosa V . Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering. Stem Cells Int. 2015; 2015:804213. PMC: 4466492. DOI: 10.1155/2015/804213. View

12.

Jarvinen P, Hamalainen S, Banerjee K, Hakkinen P, Ijas M, Harju A . Molecular self-assembly on graphene on SiO2 and h-BN substrates. Nano Lett. 2013; 13(7):3199-204. DOI: 10.1021/nl401265f. View

13.

Podila R, Moore T, Alexis F, Rao A . Graphene coatings for biomedical implants. J Vis Exp. 2013; (73):e50276. PMC: 3622089. DOI: 10.3791/50276. View

14.

McMahon R, Ma J, Verkhoturov S, Munoz-Pinto D, Karaman I, Rubitschek F . A comparative study of the cytotoxicity and corrosion resistance of nickel-titanium and titanium-niobium shape memory alloys. Acta Biomater. 2012; 8(7):2863-70. DOI: 10.1016/j.actbio.2012.03.034. View

15.

Lotya M, King P, Khan U, De S, Coleman J . High-concentration, surfactant-stabilized graphene dispersions. ACS Nano. 2010; 4(6):3155-62. DOI: 10.1021/nn1005304. View

16.

Teng P, Lu C, Akiyama-Hasegawa K, Lin Y, Yeh C, Suenaga K . Remote catalyzation for direct formation of graphene layers on oxides. Nano Lett. 2012; 12(3):1379-84. DOI: 10.1021/nl204024k. View

17.

Cheng J, Liu J, Wu B, Liu Z, Li M, Wang X . Graphene and its Derivatives for Bone Tissue Engineering: and Evaluation of Graphene-Based Scaffolds, Membranes and Coatings. Front Bioeng Biotechnol. 2021; 9:734688. PMC: 8511325. DOI: 10.3389/fbioe.2021.734688. View

18.

Banerjee A . Graphene and its derivatives as biomedical materials: future prospects and challenges. Interface Focus. 2018; 8(3):20170056. PMC: 5915658. DOI: 10.1098/rsfs.2017.0056. View

19.

Nishida E, Miyaji H, Kato A, Takita H, Iwanaga T, Momose T . Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket. Int J Nanomedicine. 2016; 11:2265-77. PMC: 4887064. DOI: 10.2147/IJN.S104778. View

20.

Wang Q, Hersam M . Room-temperature molecular-resolution characterization of self-assembled organic monolayers on epitaxial graphene. Nat Chem. 2011; 1(3):206-11. DOI: 10.1038/nchem.212. View