Association of Delayed Initiation of Non-invasive Respiratory Support with Pulmonary Air Leakage in Outborn Late-preterm and Term Neonates

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2022 Jan 10

PMID 35006375

Authors

Eui Kyung Choi

Kyu Hee Park

Byung Min Choi

Affiliations

Soon will be listed here.

Abstract

Conclusion: Our study shows that outborn neonates with moderate-to-severe RD, who were treated with delayed non-invasive respiratory support, were associated with an increased likelihood of pulmonary air leakage. Additional prospective studies are required to establish the optimal timing and methods of non-invasive respiratory support for outborn, late-preterm, and term infants.

What Is Known: • Non-invasive respiratory support is widely used in neonates of all gestational ages. • Little is known on the impact of delayed initiation of non-invasive respiratory support in outborn, late preterm, and term neonates.

What Is New: • Male sex, high oxygen requirement (FiO2 >0.3), high initial CO2 level, and respiratory distress syndrome significantly correlated with adverse outcomes. • Outborn late-preterm and term neonates with high oxygen requirement who were treated with delayed non-invasive respiratory support indicated an increased likelihood of pulmonary air leakage.

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