» Articles » PMID: 34993440

Use of Race, Ethnicity, and National Origin in Studies Assessing Cardiovascular Risk in Women With a History of Hypertensive Disorders of Pregnancy

Overview
Journal CJC Open
Date 2022 Jan 7
PMID 34993440
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Women with a history of hyperBtensive disorders of pregnancy (HDP) are at particularly high risk for cardiovascular disease (CVD) and CVD-related death, and certain racial and ethnic subpopulations are disproportionately affected by these conditions. We examined the use of race, ethnicity, and national origin in observational studies assessing CVD morbidity and mortality in women with a history of HDP. A total of 124 studies, published between 1976 and 2021, were reviewed. We found that white women were heavily overrepresented, encompassing 53% of all participants with HDP. There was limited and heterogeneous reporting of race and ethnicity information across studies and only 27 studies reported including race and/or ethnicity variables in at least 1 statistical analysis. Only 2 studies mentioned the use of these variables as a strength; several others (k = 18) reported a lack of diversity among participants as a study limitation. Just over half of included articles (k = 68) reported at least 1 sociodemographic variable other than race and ethnicity (eg, marital status and income); however, none investigated how they might have worked synergistically or antagonistically with race and/or ethnicity to influence participants' risk of CVD. These findings highlight significant areas for improvement in cardiovascular obstetrics research, including the need for more robust and standardized methods for collecting, reporting, and using sociodemographic information. Future studies of CVD risk in women with a history of HDP should explicitly examine racial and ethnic differences and use an intersectional approach.

Citing Articles

Addressing Known hypertensive disOrders of pregnancy in woMen of African descent in Canada (AKOMA): protocol for a mixed method study.

Baiden D, Nerenberg K, Hillan E, Dogba M, Parry M Front Cardiovasc Med. 2024; 11:1471199.

PMID: 39736880 PMC: 11683087. DOI: 10.3389/fcvm.2024.1471199.


Long-term cardiovascular outcome in women with preeclampsia in Korea: a large population-based cohort study and meta-analysis.

Choi E, Jung Y, Kim D, Cho S, Park E, Park C Sci Rep. 2024; 14(1):7480.

PMID: 38553468 PMC: 10980767. DOI: 10.1038/s41598-024-57858-6.


Hypertension in Pregnancy: Current Challenges and Future Opportunities for Surveillance and Research.

Kuklina E, Merritt R, Wright J, Vaughan A, Coronado F J Womens Health (Larchmt). 2024; 33(5):553-562.

PMID: 38529887 PMC: 11260429. DOI: 10.1089/jwh.2023.1072.


The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 7: Sex, Gender, and the Social Determinants of Health.

Norris C, Mullen K, Foulds H, Jaffer S, Nerenberg K, Gulati M CJC Open. 2024; 6(2Part B):205-219.

PMID: 38487069 PMC: 10935698. DOI: 10.1016/j.cjco.2023.07.013.


Systematic review of validated case definitions to identify hypertensive disorders of pregnancy in administrative healthcare databases.

Johnston A, Dancey S, Tseung V, Skidmore B, Tanuseputro P, Smith G Open Heart. 2023; 10(2).

PMID: 37567603 PMC: 10423835. DOI: 10.1136/openhrt-2022-002151.


References
1.
Miller E, Boehme A, Chung N, Wang S, Lacey Jr J, Lakshminarayan K . Aspirin reduces long-term stroke risk in women with prior hypertensive disorders of pregnancy. Neurology. 2018; 92(4):e305-e316. PMC: 6345119. DOI: 10.1212/WNL.0000000000006815. View

2.
Kaaja R, Kinnunen T, Luoto R . Regional differences in the prevalence of pre-eclampsia in relation to the risk factors for coronary artery disease in women in Finland. Eur Heart J. 2004; 26(1):44-50. DOI: 10.1093/eurheartj/ehi015. View

3.
Diehl C, Brost B, Hogan M, Elesber A, Offord K, Turner S . Preeclampsia as a risk factor for cardiovascular disease later in life: validation of a preeclampsia questionnaire. Am J Obstet Gynecol. 2008; 198(5):e11-3. DOI: 10.1016/j.ajog.2007.09.038. View

4.
Marin R, Gorostidi M, Portal C, Sanchez M, Sanchez E, Alvarez J . Long-term prognosis of hypertension in pregnancy. Hypertens Pregnancy. 2000; 19(2):199-209. DOI: 10.1081/prg-100100136. View

5.
Ross P, Hart-Johnson T, Santen S, Bibler Zaidi N . Considerations for using race and ethnicity as quantitative variables in medical education research. Perspect Med Educ. 2020; 9(5):318-323. PMC: 7550522. DOI: 10.1007/s40037-020-00602-3. View