Knowledge-based Planning Using Pseudo-structures for Volumetric Modulated Arc Therapy (VMAT) of Postoperative Uterine Cervical Cancer: a Multi-institutional Study

Overview

Journal Rep Pract Oncol Radiother

Specialty Oncology

Date 2022 Jan 7

PMID 34992856

Citations 2

Authors

Tatsuya Kamima

Yoshihiro Ueda

Jun-Ichi Fukunaga

Mikoto Tamura

Yumiko Shimizu

Yuta Muraki

Yasuo Yoshioka

Nozomi Kitamura

Yuya Nitta

Masakazu Otsuka

Hajime Monzen

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this study was to investigate the performance of the RapidPlan (RP ) using models registered pseudostructures, and to determine how many structures are required for automatic optimization of volumetric modulated arc therapy (VMAT) for postoperative uterine cervical cancer.

Materials And Methods: Pseudo-structures around the PTV were retrospectively contoured for patients who had completed treatment at five institutions. For 22 common patients, plans were generated with a single optimization for models with two (RP_2), four (RP_4), and five (RP_5) registered structures, and the dosimetric parameters of these models were compared with a clinical plan with several optimizations.

Results: Most dosimetric parameters showed no major differences between each RP model. In particular, the rectum D, V, and V with RP_2, RP_4, and RP_5 were not significantly different, and were lower than those of the clinical plan. The average proportions of plans achieving acceptable criteria for dosimetric parameters were close to 100% for all models. Using RP_2, the average time for the VMAT planning was reduced by 88 minutes compared with the clinical plan.

Conclusion: The RapidPlan model with two registered pseudo-structures could generate clinically acceptable plans while saving time.

Citing Articles

Differences between professionals in treatment planning for patients with stage III lung cancer using treatment-planning QA software.

Sato D, Sasaki M, Nakaguchi Y, Kamomae T, Kawanaka T, Kubo A Rep Pract Oncol Radiother. 2024; 28(5):671-680.

PMID: 38179286 PMC: 10764038. DOI: 10.5603/rpor.97511.

Multi-institution model (big model) versus single-institution model of knowledge-based volumetric modulated arc therapy (VMAT) planning for prostate cancer.

Fukunaga J, Tamura M, Ueda Y, Kamima T, Shimizu Y, Muraki Y Sci Rep. 2022; 12(1):15282.

PMID: 36088382 PMC: 9464226. DOI: 10.1038/s41598-022-19498-6.

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