Prevalence and Predictors of Hypovitaminosis D in Ethiopian HIV-Infected Adults

Overview

Journal HIV AIDS (Auckl)

Publisher Dove Medical Press

Specialty Infectious Diseases

Date 2022 Jan 7

PMID 34992468

Citations 1

Authors

Abebe Muche Belete

Alemu Adela Tefera

Mekasha Getnet

Adisu Asefa

Yared Asmare Aynalem

Wondimeneh Shibabaw Shiferaw

Affiliations

Soon will be listed here.

Abstract

Background: Hypovitaminosis D is associated with bone fracture and cardiovascular disease in patients receiving antiretroviral therapy. Currently, there are few data on the magnitude of hypovitaminosis D in people living with HIV in Sub-Saharan country. Therefore, the present study determines the magnitude of hypovitaminosis D in people living with HIV and its associated factors in Ethiopia.

Methods: A cross-sectional study was conducted among 171 adult people living with HIV at Debre Berhan Specialized Hospital. Serum vitamin D was measured. Multivariate logistic regression analysis and p-value <0.05 was used to identify the associated factors of hypovitaminosis D.

Results: In the present study, the prevalence of hypovitaminosis D was 129/171 (75.4%), with 11/171 (6.4%) having vitamin D deficiency and 118/171 (69%) having vitamin D insufficiency. Female sex was significantly associated with hypovitaminosis D (AOR: 3.01, 95% CI = 1.381-6.561, P = 0.006).

Conclusion: Our study found a high burden of hypovitaminosis D among adult people living with HIV on antiretroviral therapy. Female sex was associated with hypovitaminosis D.

Citing Articles

Circulating 25-hydroxycholecalciferol and calcium levels, and alkaline phosphatase activity among people living with and without human immunodeficiency virus and injecting drugs in kenya.

Onyango A, Shaviya N, Budambula V, Orinda G, Anzala O, Aabid A BMC Infect Dis. 2024; 24(1):703.

PMID: 39020290 PMC: 11256408. DOI: 10.1186/s12879-024-09610-8.

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