Vascular Anomalies: Clinical Perspectives

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2022 Jan 5

PMID 34984511

Citations 4

Authors

Joao Guilherme Amaral

Irene Lara-Corrales

Affiliations

Soon will be listed here.

Abstract

Vascular anomalies are classified as vascular tumors or vascular malformations according to their cellular features and biological behavior. Detailed history and clinical assessment allow for the proper clinical diagnosis of most vascular anomalies and guide the choice of imaging to evaluate them. This article discusses the general information needed from a clinical history and physical exam to formulate a diagnosis of vascular anomaly. Then, the authors review the clinical findings from the most common vascular tumors and vascular malformations.

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References

Zuniga-Castillo M, Teng C, Teng J . Genetics of vascular malformation and therapeutic implications. Curr Opin Pediatr. 2019; 31(4):498-508. DOI: 10.1097/MOP.0000000000000794. View

Tekes A, Koshy J, Kalayci T, Puttgen K, Cohen B, Redett R . S.E. Mitchell Vascular Anomalies Flow Chart (SEMVAFC): a visual pathway combining clinical and imaging findings for classification of soft-tissue vascular anomalies. Clin Radiol. 2014; 69(5):443-57. DOI: 10.1016/j.crad.2013.11.016. View

Van Damme A, Seront E, Dekeuleneer V, Boon L, Vikkula M . New and Emerging Targeted Therapies for Vascular Malformations. Am J Clin Dermatol. 2020; 21(5):657-668. DOI: 10.1007/s40257-020-00528-w. View

Hoornweg M, Smeulders M, Ubbink D, van der Horst C . The prevalence and risk factors of infantile haemangiomas: a case-control study in the Dutch population. Paediatr Perinat Epidemiol. 2012; 26(2):156-62. DOI: 10.1111/j.1365-3016.2011.01214.x. View

North P, Waner M, Mizeracki A, Mihm Jr M . GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. Hum Pathol. 2000; 31(1):11-22. DOI: 10.1016/s0046-8177(00)80192-6. View

Amir J, Metzker A, Krikler R, REISNER S . Strawberry hemangioma in preterm infants. Pediatr Dermatol. 1986; 3(4):331-2. DOI: 10.1111/j.1525-1470.1986.tb00535.x. View

Bruckner A, Frieden I . Hemangiomas of infancy. J Am Acad Dermatol. 2003; 48(4):477-93; quiz 494-6. DOI: 10.1067/mjd.2003.200. View

Chang L, Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M . Growth characteristics of infantile hemangiomas: implications for management. Pediatrics. 2008; 122(2):360-7. DOI: 10.1542/peds.2007-2767. View

Couto R, Maclellan R, Zurakowski D, Greene A . Infantile hemangioma: clinical assessment of the involuting phase and implications for management. Plast Reconstr Surg. 2012; 130(3):619-624. DOI: 10.1097/PRS.0b013e31825dc129. View

10.

Metry D, Haggstrom A, Drolet B, Baselga E, Chamlin S, Garzon M . A prospective study of PHACE syndrome in infantile hemangiomas: demographic features, clinical findings, and complications. Am J Med Genet A. 2006; 140(9):975-86. DOI: 10.1002/ajmg.a.31189. View

11.

Frieden I, Reese V, Cohen D . PHACE syndrome. The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities. Arch Dermatol. 1996; 132(3):307-11. DOI: 10.1001/archderm.132.3.307. View

12.

Metry D, Heyer G, Hess C, Garzon M, Haggstrom A, Frommelt P . Consensus Statement on Diagnostic Criteria for PHACE Syndrome. Pediatrics. 2009; 124(5):1447-56. DOI: 10.1542/peds.2009-0082. View

13.

Garzon M, Epstein L, Heyer G, Frommelt P, Orbach D, Baylis A . PHACE Syndrome: Consensus-Derived Diagnosis and Care Recommendations. J Pediatr. 2016; 178:24-33.e2. PMC: 6599593. DOI: 10.1016/j.jpeds.2016.07.054. View

14.

Girard C, Bigorre M, Guillot B, Bessis D . PELVIS Syndrome. Arch Dermatol. 2006; 142(7):884-8. DOI: 10.1001/archderm.142.7.884. View

15.

Iacobas I, Burrows P, Frieden I, Liang M, Mulliken J, Mancini A . LUMBAR: association between cutaneous infantile hemangiomas of the lower body and regional congenital anomalies. J Pediatr. 2010; 157(5):795-801.e1-7. DOI: 10.1016/j.jpeds.2010.05.027. View

16.

Hughes J, Hill V, Patel K, Syed S, Harper J, De Bruyn R . Cutaneous haemangioma: prevalence and sonographic characteristics of associated hepatic haemangioma. Clin Radiol. 2004; 59(3):273-80. DOI: 10.1016/S0009-9260(03)00267-8. View

17.

Mulliken J, Fishman S, Burrows P . Vascular anomalies. Curr Probl Surg. 2000; 37(8):517-84. DOI: 10.1016/s0011-3840(00)80013-1. View

18.

Restrepo R, Palani R, Cervantes L, Duarte A, Amjad I, Altman N . Hemangiomas revisited: the useful, the unusual and the new. Part 1: overview and clinical and imaging characteristics. Pediatr Radiol. 2011; 41(7):895-904. DOI: 10.1007/s00247-011-2076-5. View

19.

Berenguer B, Mulliken J, Enjolras O, Boon L, Wassef M, Josset P . Rapidly involuting congenital hemangioma: clinical and histopathologic features. Pediatr Dev Pathol. 2004; 6(6):495-510. DOI: 10.1007/s10024-003-2134-6. View

20.

Krol A, Macarthur C . Congenital hemangiomas: rapidly involuting and noninvoluting congenital hemangiomas. Arch Facial Plast Surg. 2005; 7(5):307-11. DOI: 10.1001/archfaci.7.5.307. View