Therapeutic Application of RTMS in Atypical Parkinsonian Disorders

Overview

Journal Behav Neurol

Publisher Wiley

Specialty Psychiatry

Date 2022 Jan 3

PMID 34976231

Citations 1

Authors

Chrysi Petsani

Athina-Maria Aloizou

Vasileios Siokas

Lambros Messinis

Eleni Peristeri

Christos Bakirtzis

Grigorios Nasios

Efthimios Dardiotis

Affiliations

Soon will be listed here.

Abstract

The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (LBD). APDs are characterized by a variety of symptoms and a lack of disease modifying therapies; their treatment thus remains mainly symptomatic. Brain stimulation via repetitive transcranial magnetic stimulation (rTMS) is a safe and noninvasive intervention using a magnetic coil, and it is considered an alternative therapy in various neuropsychiatric pathologies. In this paper, we review the available studies that investigate the efficacy of rTMS in the treatment of these APDs and Parkinson plus syndromes. he majority of the studies have shown beneficial effects on motor and nonmotor symptoms, but research is still at a preliminary phase, with large, double-blind studies lacking in the literature.

Citing Articles

The Role of Non-Invasive Brain Modulation in Identifying Disease Biomarkers for Diagnostic and Therapeutic Purposes in Parkinsonism.

Birreci D, De Riggi M, Costa D, Angelini L, Cannavacciuolo A, Passaretti M Brain Sci. 2024; 14(7).

PMID: 39061435 PMC: 11274666. DOI: 10.3390/brainsci14070695.

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