Antimicrobial Resistance in Bovine Respiratory Disease: Auction Market- and Ranch-raised Calves

Overview

Journal Can Vet J

Specialty Veterinary Medicine

Date 2022 Jan 3

PMID 34975167

Citations 5

Authors

Trent R Wennekamp

Cheryl L Waldner

M Claire Windeyer

Kathy Larson

Anatoliy Trokhymchuk

John R Campbell

Affiliations

Soon will be listed here.

Abstract

This study compared changes in prevalence and antimicrobial susceptibility of , and in feedlot calves derived from the auction market (AUCT; = 299) and from a single-ranch source (RANCH; = 300). In the AUCT calves, the prevalence of decreased, whereas increased over the feeding period. The AUCT calves showed an increase in isolates not susceptible to tulathromycin for all bovine respiratory disease (BRD) pathogens, an increase in and isolates not susceptible to oxytetracycline, and an increase in isolates not susceptible to florfenicol. In the RANCH calves, the prevalence of all 3 BRD pathogens was high at feedlot entry and decreased significantly during the study period. In RANCH calves, there was a significant increase in isolates not susceptible to oxytetracycline, tulathromycin, and florfenicol. Surprisingly, there was a significant decrease in isolates that were not susceptible to oxytetracycline, tilmicosin, and tulathromycin.

Citing Articles

Contagious acquisition of antimicrobial resistance is critical for explaining emergence in western Canadian feedlots-insights from an agent-based modelling tool.

Ramsay D, McDonald W, Thompson M, Erickson N, Gow S, Osgood N Front Vet Sci. 2025; 11:1466986.

PMID: 39867600 PMC: 11758982. DOI: 10.3389/fvets.2024.1466986.

Pasteurella multocida from deep nasal swabs and tracheobronchial lavage in bovine calves from Sweden.

Myrenas M, Pringle M, Harbom B, Bengtsson B Acta Vet Scand. 2024; 66(1):58.

PMID: 39501282 PMC: 11539715. DOI: 10.1186/s13028-024-00781-7.

Synthetic antimicrobial peptides Bac-5, BMAP-28, and Syn-1 can inhibit bovine respiratory disease pathogens .

Cornejo S, Barber C, Thoresen M, Lawrence M, Seo K, Woolums A Front Vet Sci. 2024; 11:1430919.

PMID: 39188903 PMC: 11345158. DOI: 10.3389/fvets.2024.1430919.

Association between respiratory disease pathogens in calves near feedlot arrival with treatment for bovine respiratory disease and subsequent antimicrobial resistance status.

Abi Younes J, Campbell J, Gow S, Woolums A, Waldner C Front Vet Sci. 2024; 11:1416436.

PMID: 39109351 PMC: 11300316. DOI: 10.3389/fvets.2024.1416436.

Complete circular assembly of PDS1537697-81-1 genome and phenotypic characterization of its antibiotic susceptibility.

Trokhymchuk A, Erickson N, Waldner C, Links M Microbiol Resour Announc. 2024; 13(6):e0017024.

PMID: 38738930 PMC: 11326112. DOI: 10.1128/mra.00170-24.

References

Timsit E, Hallewell J, Booker C, Tison N, Amat S, Alexander T . Prevalence and antimicrobial susceptibility of Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni isolated from the lower respiratory tract of healthy feedlot cattle and those diagnosed with bovine respiratory disease. Vet Microbiol. 2017; 208:118-125. DOI: 10.1016/j.vetmic.2017.07.013. View

Anholt R, Klima C, Allan N, Matheson-Bird H, Schatz C, Ajitkumar P . Antimicrobial Susceptibility of Bacteria That Cause Bovine Respiratory Disease Complex in Alberta, Canada. Front Vet Sci. 2017; 4:207. PMC: 5723070. DOI: 10.3389/fvets.2017.00207. View

Watts J, Yancey Jr R, Salmon S, Case C . A 4-year survey of antimicrobial susceptibility trends for isolates from cattle with bovine respiratory disease in North America. J Clin Microbiol. 1994; 32(3):725-31. PMC: 263115. DOI: 10.1128/jcm.32.3.725-731.1994. View

Ribble C, Meek A, Shewen P, Guichon P, Jim G . Effect of pretransit mixing on fatal fibrinous pneumonia in calves. J Am Vet Med Assoc. 1995; 207(5):616-9. View

Allen J, Viel L, Bateman K, Rosendal S . Changes in the bacterial flora of the upper and lower respiratory tracts and bronchoalveolar lavage differential cell counts in feedlot calves treated for respiratory diseases. Can J Vet Res. 1992; 56(3):177-83. PMC: 1263534. View

Klima C, Alexander T, Read R, Gow S, Booker C, Hannon S . Genetic characterization and antimicrobial susceptibility of Mannheimia haemolytica isolated from the nasopharynx of feedlot cattle. Vet Microbiol. 2010; 149(3-4):390-8. DOI: 10.1016/j.vetmic.2010.11.018. View

Timsit E, Workentine M, Crepieux T, Miller C, Regev-Shoshani G, Schaefer A . Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. Res Vet Sci. 2017; 115:117-124. DOI: 10.1016/j.rvsc.2017.02.001. View

Step D, Krehbiel C, DePra H, Cranston J, Fulton R, Kirkpatrick J . Effects of commingling beef calves from different sources and weaning protocols during a forty-two-day receiving period on performance and bovine respiratory disease. J Anim Sci. 2008; 86(11):3146-58. DOI: 10.2527/jas.2008-0883. View

Woolums A, Karisch B, Frye J, Epperson W, Smith D, Blanton Jr J . Multidrug resistant Mannheimia haemolytica isolated from high-risk beef stocker cattle after antimicrobial metaphylaxis and treatment for bovine respiratory disease. Vet Microbiol. 2018; 221:143-152. DOI: 10.1016/j.vetmic.2018.06.005. View

10.

Stroebel C, Alexander T, Workentine M, Timsit E . Effects of transportation to and co-mingling at an auction market on nasopharyngeal and tracheal bacterial communities of recently weaned beef cattle. Vet Microbiol. 2018; 223:126-133. DOI: 10.1016/j.vetmic.2018.08.007. View

11.

Taylor J, Holland B, Step D, Payton M, Confer A . Nasal isolation of Mannheimia haemolytica and Pasteurella multocida as predictors of respiratory disease in shipped calves. Res Vet Sci. 2015; 99:41-5. DOI: 10.1016/j.rvsc.2014.12.015. View

12.

Welsh R, Dye L, Payton M, Confer A . Isolation and antimicrobial susceptibilities of bacterial pathogens from bovine pneumonia: 1994--2002. J Vet Diagn Invest. 2004; 16(5):426-31. DOI: 10.1177/104063870401600510. View

13.

Portis E, Lindeman C, Johansen L, Stoltman G . A ten-year (2000-2009) study of antimicrobial susceptibility of bacteria that cause bovine respiratory disease complex--Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni--in the United States and Canada. J Vet Diagn Invest. 2012; 24(5):932-44. DOI: 10.1177/1040638712457559. View

14.

Guo Y, McMullen C, Timsit E, Hallewell J, Orsel K, van der Meer F . Genetic relatedness and antimicrobial resistance in respiratory bacteria from beef calves sampled from spring processing to 40 days after feedlot entry. Vet Microbiol. 2020; 240:108478. DOI: 10.1016/j.vetmic.2019.108478. View

15.

Snyder E, Credille B, Berghaus R, Giguere S . Prevalence of multi drug antimicrobial resistance in isolated from high-risk stocker cattle at arrival and two weeks after processing. J Anim Sci. 2017; 95(3):1124-1131. DOI: 10.2527/jas.2016.1110. View

16.

Jorgensen J, Ferraro M . Antimicrobial susceptibility testing: a review of general principles and contemporary practices. Clin Infect Dis. 2009; 49(11):1749-55. DOI: 10.1086/647952. View

17.

Noyes N, Benedict K, Gow S, Booker C, Hannon S, McAllister T . Mannheimia haemolytica in feedlot cattle: prevalence of recovery and associations with antimicrobial use, resistance, and health outcomes. J Vet Intern Med. 2015; 29(2):705-13. PMC: 4895489. DOI: 10.1111/jvim.12547. View