Current Status on Extracellular Vesicles from the Dimorphic Pathogenic Species of Paracoccidioides

Overview

Journal Curr Top Microbiol Immunol

Specialties Allergy & Immunology
Microbiology

Date 2022 Jan 1

PMID 34972875

Citations 1

Authors

Rosana Puccia

Affiliations

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Abstract

Species of the Paracoccidioides brasiliensis complex and P. lutzii cause human paracoccidioidomycosis (PCM). Early interest in Paracoccidioides extracellular vesicles (EVs) resulted in a series of publications that unraveled the EVs protein, carbohydrate, lipid, and RNA cargo from isolates of different phylogenetic groups and distinct virulence degrees. EV and cell wall components were compared. These works are discussed in parallel with more recent data on the role of Paracoccidioides EVs in immunomodulation.

Citing Articles

Extracellular Vesicles From Can Induce the Expression of Fungal Virulence Traits and Enhance Infection in Mice.

Octaviano C, Abrantes N, Puccia R Front Cell Infect Microbiol. 2022; 12:834653.

PMID: 35295759 PMC: 8918656. DOI: 10.3389/fcimb.2022.834653.

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