Anion-Dependent Synthesis of Cu(II) Complexes with 2-(1-Tetrazol-5-yl)-1-indole: Synthesis, X-Ray Structures, and Radical Scavenging Activity

Overview

Journal Bioinorg Chem Appl

Publisher Wiley

Date 2021 Dec 31

PMID 34970307

Authors

Petr Halas

Juraj Kuchar

Radovan Herchel

Affiliations

Soon will be listed here.

Abstract

Two mononuclear Cu(II) complexes, [Cu(phen)(HL)]ClO·HO·2DMF () and [Cu(phen)(HL)]·EtOH (), comprising 1,10-phentantroline (phen) and 2-(1-tetrazol-5-yl)-1-indole ligand (HL) ligands are reported. Analysis and characterization of the samples were performed using standard physicochemical techniques, elemental analysis, nuclear magnetic resonance, Fourier transform infrared spectroscopy, and UV-vis spectroscopy. Single-crystal X-ray crystallography revealed the formation of a pentacoordinate complex in and a hexacoordinate complex in , in which the anionic ligand HL has undergone monodentate coordination through the tetrazole unit. Furthermore, the crystal structure of HL·MeOH is also discussed. The potential application of compounds and in bioinorganic chemistry was addressed by investigating their radical scavenging activity with the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) and the results were supported also by theoretical calculations.

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