Dietary Use of Artemisia Herba Alba Asso As a Potential Coccidiostat Against Cæcal Coccidiosis: Haematological Parameter Variations

Overview

Journal Trop Anim Health Prod

Publisher Springer

Specialties Tropical Medicine
Veterinary Medicine

Date 2021 Dec 28

PMID 34961903

Authors

Ahmed Messai

Sara Redouane-Salah

Affiliations

Soon will be listed here.

Abstract

This study consists of the evaluation of the anticoccidial effect of Artemisia herba-alba Asso during experimental coccidial infection. Four groups of 30 broiler chickens were formed: the negative control (G1), the positive control (G2), the infected Monensin-treated group (G3), and the infected Artemisia-treated group (G4). Each infected bird received orally 10 sporulated oocysts of Eimeria tenella. No mortality was recorded in both G1 and G4. Haematocrit levels showed great variations from the 7th day post-infection, especially in G2 (20.87% ± 5.77). By day 10 P-I, haematocrit recovery was rapid particularly in G4 (28.07% ± 1.50). Haemoglobin concentration also decreased significantly (p < 0.05) in all infected groups by the 7th day P-I. The reduction was very marked, but not statistically significant, in G2 (6.47 g/dL ± 1.67) against (10.53 g/dL ± 0.25) in G1. It was less marked in G4 (8.05 g/dL ± 1.56). Results show the protective effect of A. herba-alba Asso by improving the lesion score and the haematological parameters affected during coccidian infection.

References

Allen P, Lydon J, Danforth H . Effects of components of Artemisia annua on coccidia infections in chickens. Poult Sci. 1997; 76(8):1156-63. DOI: 10.1093/ps/76.8.1156. View

de Almeida G, Horsted K, Thamsborg S, Kyvsgaard N, Ferreira J, Hermansen J . Use of Artemisia annua as a natural coccidiostat in free-range broilers and its effects on infection dynamics and performance. Vet Parasitol. 2011; 186(3-4):178-87. DOI: 10.1016/j.vetpar.2011.11.058. View

Arab H, Rahbari S, Rassouli A, Moslemi M, Khosravirad F . Determination of artemisinin in Artemisia sieberi and anticoccidial effects of the plant extract in broiler chickens. Trop Anim Health Prod. 2007; 38(6):497-503. DOI: 10.1007/s11250-006-4390-8. View

Covello P, Teoh K, Polichuk D, Reed D, Nowak G . Functional genomics and the biosynthesis of artemisinin. Phytochemistry. 2007; 68(14):1864-71. DOI: 10.1016/j.phytochem.2007.02.016. View

Del Cacho E, Gallego M, Francesch M, Quilez J, Sanchez-Acedo C . Effect of artemisinin on oocyst wall formation and sporulation during Eimeria tenella infection. Parasitol Int. 2010; 59(4):506-11. DOI: 10.1016/j.parint.2010.04.001. View

Giannenas I, Florou-Paneri P, Papazahariadou M, Christaki E, Botsoglou N, Spais A . Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella. Arch Tierernahr. 2003; 57(2):99-106. DOI: 10.1080/0003942031000107299. View

Habibi H, Firouzi S, Nili H, Razavi M, Asadi S, Daneshi S . Anticoccidial effects of herbal extracts on Eimeria tenella infection in broiler chickens: in vitro and in vivo study. J Parasit Dis. 2016; 40(2):401-7. PMC: 4927499. DOI: 10.1007/s12639-014-0517-4. View

Jiao J, Yang Y, Liu M, Li J, Cui Y, Yin S . Artemisinin and Artemisia annua leaves alleviate Eimeria tenella infection by facilitating apoptosis of host cells and suppressing inflammatory response. Vet Parasitol. 2018; 254:172-177. DOI: 10.1016/j.vetpar.2018.03.017. View

Johnson J, REID W . Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens. Exp Parasitol. 1970; 28(1):30-6. DOI: 10.1016/0014-4894(70)90063-9. View

10.

Kaboutari J, Arab H, Ebrahimi K, Rahbari S . Prophylactic and therapeutic effects of a novel granulated formulation of Artemisia extract on broiler coccidiosis. Trop Anim Health Prod. 2013; 46(1):43-8. DOI: 10.1007/s11250-013-0444-x. View

11.

Lu F, He X, Richard C, Cao J . A brief history of artemisinin: Modes of action and mechanisms of resistance. Chin J Nat Med. 2019; 17(5):331-336. DOI: 10.1016/S1875-5364(19)30038-X. View

12.

Machin L, Napoles R, Gille L, Monzote L . Leishmania amazonensis response to artemisinin and derivatives. Parasitol Int. 2020; 80:102218. DOI: 10.1016/j.parint.2020.102218. View

13.

Meshnick S . Artemisinin: mechanisms of action, resistance and toxicity. Int J Parasitol. 2002; 32(13):1655-60. DOI: 10.1016/s0020-7519(02)00194-7. View

14.

Moraes P, Cardinal K, Gouvea F, Schroeder B, Ceron M, Lunedo R . Comparison between a commercial blend of functional oils and monensin on the performance and microbiota of coccidiosis-challenged broilers. Poult Sci. 2019; 98(11):5456-5464. DOI: 10.3382/ps/pez345. View

15.

Kheirabadi K, Kaboutari Katadj J, Bahadoran S, Teixeira da Silva J, Samani A, Bashi M . Comparison of the anticoccidial effect of granulated extract of Artemisia sieberi with monensin in experimental coccidiosis in broiler chickens. Exp Parasitol. 2014; 141:129-33. DOI: 10.1016/j.exppara.2014.03.022. View

16.

Williams R . A compartmentalised model for the estimation of the cost of coccidiosis to the world's chicken production industry. Int J Parasitol. 1999; 29(8):1209-29. DOI: 10.1016/s0020-7519(99)00086-7. View

17.

Youn H, Noh J . Screening of the anticoccidial effects of herb extracts against Eimeria tenella. Vet Parasitol. 2001; 96(4):257-63. DOI: 10.1016/s0304-4017(01)00385-5. View

18.

Zaman M, Iqbal Z, Abbas R, Khan M . Anticoccidial activity of herbal complex in broiler chickens challenged with Eimeria tenella. Parasitology. 2011; 139(2):237-43. DOI: 10.1017/S003118201100182X. View