The Connectome from the Cerebral Cortex to the Viscera Using Viral Transneuronal Tracers

Overview

Journal Am J Transl Res

Specialty General Medicine

Date 2021 Dec 27

PMID 34956443

Citations 4

Authors

Zhixiao Li

Zhen Li

Weiguo Xu

Yujuan Li

Qian Wang

Hui Xu

Anne Manyande

Duozhi Wu

Maohui Feng

Hongbing Xiang

Affiliations

Soon will be listed here.

Abstract

As an emerging framework in neuroscience, brain connectomics is well suited for investigating key questions on brain complexity by combining viral transneuronal tracing and whole brain graphic methodologies using analytical tools of network science. Transsynaptic viral tract-tracing in the toolbox of neural labeling methods has been a significant development in the connectomics field to decipher the circuit-level architecture of the cerebral cortex. In the present work, we reviewed the current methods enabling structural connectivity from the viscera to the cerebral cortex mapping with viral transneuronal tracers and showed how such neuroanatomic connectomic data could be used to infer new structural and functional information in viscera-cerebral cortex circuits.

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