Analysis of Serum Biochemical Indexes, Egg Quality, and Liver Transcriptome in Laying Hens Fed Diets Supplemented with Powder

Overview

Journal Genes (Basel)

Publisher MDPI

Date 2021 Dec 24

PMID 34946891

Citations 1

Authors

Tao Li

Shuya Zhang

Jiqiao Zhang

Yiping Song

Xiuyu Bao

Fengwen Xu

Jianqin Zhang

Affiliations

Soon will be listed here.

Abstract

(), known as "southern ginseng", can reduce the blood pressure and blood lipid levels. In this study, 300 layer chicks of one day old were divided randomly into three groups (control group (base diet), high addition group (base diet with 1% ), and low addition group (base diet with 0.5% )). After 29 weeks, the growth performance, egg quality, and serum index were determined. Additionally, liver mRNA was identified using RNA-seq to investigate the molecular mechanisms. The results indicated that the serum total cholesterol and triglycerides decreased significantly in the addition group. The addition of increased the egg weight, Haugh unit and redness (a*) of the egg yolk color, and reduced the yolk cholesterol concentration. Moreover, 95 differentially expressed genes (DEGs) were screened between the control and addition group. GO and the KEGG analysis showed that the PPAR pathway was significantly enriched. Five fatty acid metabolism-related genes (, , , , and ) were validated by qRT-PCR analysis, which confirmed the tendency of the expression. These DEGs in the PPAR pathway may be the key factors of affecting fatty acid metabolism. These results may provide a theoretical basis for further research and new insights into as a feed additive.

Citing Articles

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PMID: 36139338 PMC: 9495209. DOI: 10.3390/ani12182480.

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