Orthobiologics: Diagnosis and Treatment of Common Tendinopathies

Overview

Journal Semin Musculoskelet Radiol

Publisher Thieme

Specialties Orthopedics
Physiology
Radiology

Date 2021 Dec 22

PMID 34937114

Citations 7

Authors

Katherine D Van Schaik

Kenneth S Lee

Affiliations

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Abstract

Orthobiologics, including platelet-rich plasma, prolotherapy, and mesenchymal stem cells, are seeing increasing use in the treatment of osteoarthritis (OA), muscle injury, and tendinopathy. This article reviews the biology and applications of orthobiologics in tendons, muscles, and joints, and focuses on platelet-rich plasma (PRP). Clinical evidence-based literature related to the use of PRP in the treatment of rotator cuff injury, lateral epicondylosis, Achilles tendinopathy, plantar fasciitis, knee OA, and acute muscle injury are discussed.

Citing Articles

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Advancements in Therapeutic Approaches for Degenerative Tendinopathy: Evaluating Efficacy and Challenges.

Morya V, Shahid H, Lang J, Kwak M, Park S, Noh K Int J Mol Sci. 2024; 25(21).

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Lu K, Tang H, Wang Y, Wang L, Zhou M, He G Stem Cells Int. 2023; 2023:2915826.

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N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling.

Lu K, Zhou M, Wang L, Wang Y, Tang H, He G BMC Mol Cell Biol. 2023; 24(1):1.

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Rodriguez-Merchan E Arch Bone Jt Surg. 2022; 10(10):827-832.

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