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Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV- and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral...

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Date 2021 Dec 20
PMID 34926713
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Abstract

Final results from the long-term Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) found low rates of hepatitis C virus (HCV) recurrence after direct-acting antiviral therapy in both HCV/human immunodeficiency virus (HIV)-coinfected (0.67/100 person-years) and HCV-infected (0.2/100 person-years) groups with >500 person-years of follow-up. Confirmed reinfections were in participants with HIV who reported high-risk behaviors.

References
1.
Rossi C, Butt Z, Wong S, Buxton J, Islam N, Yu A . Hepatitis C virus reinfection after successful treatment with direct-acting antiviral therapy in a large population-based cohort. J Hepatol. 2018; 69(5):1007-1014. DOI: 10.1016/j.jhep.2018.07.025. View

2.
Ingiliz P, Martin T, Rodger A, Stellbrink H, Mauss S, Boesecke C . HCV reinfection incidence and spontaneous clearance rates in HIV-positive men who have sex with men in Western Europe. J Hepatol. 2016; 66(2):282-287. DOI: 10.1016/j.jhep.2016.09.004. View

3.
Newsum A, Matser A, Schinkel J, Van Der Valk M, Brinkman K, van Eeden A . Incidence of HCV Reinfection Among HIV-Positive MSM and Its Association With Sexual Risk Behavior: A Longitudinal Analysis. Clin Infect Dis. 2020; 73(3):460-467. DOI: 10.1093/cid/ciaa645. View

4.
Huang M, Chang S, Liu C, Cheng A, Su L, Liu W . HCV reinfections after viral clearance among HIV-positive patients with recent HCV infection in Taiwan. Liver Int. 2019; 39(10):1860-1867. DOI: 10.1111/liv.14199. View

5.
Danta M, Brown D, Bhagani S, Pybus O, Sabin C, Nelson M . Recent epidemic of acute hepatitis C virus in HIV-positive men who have sex with men linked to high-risk sexual behaviours. AIDS. 2007; 21(8):983-91. DOI: 10.1097/QAD.0b013e3281053a0c. View